Marshall MNM, et al. (2022) Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 2. Mol Biol Cell 33(12):cor4 PMID:36137247
Galez HA, et al. (2021) Phosphorylation of mRNA-Binding Proteins Puf1 and Puf2 by TORC2-Activated Protein Kinase Ypk1 Alleviates Their Repressive Effects. Membranes (Basel) 11(7) PMID:34209236
Patterson JC, et al. (2021) Cdc42-Specific GTPase-Activating Protein Rga1 Squelches Crosstalk between the High-Osmolarity Glycerol (HOG) and Mating Pheromone Response MAPK Pathways. Biomolecules 11(10) PMID:34680163
Topolska M, et al. (2020) TORC2-Dependent Ypk1-Mediated Phosphorylation of Lam2/Ltc4 Disrupts Its Association with the β-Propeller Protein Laf1 at Endoplasmic Reticulum-Plasma Membrane Contact Sites in the Yeast Saccharomyces cerevisiae. Biomolecules 10(12) PMID:33255682
Locke MN and Thorner J (2019) Regulation of TORC2 function and localization by Rab5 GTPases in Saccharomyces cerevisiae. Cell Cycle 18(10):1084-1094 PMID:31068077
Martinez Marshall MN, et al. (2019) Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 2. Mol Biol Cell 30(12):1555-1574 PMID:30969890
McMurray MA and Thorner J (2019) Turning it inside out: The organization of human septin heterooligomers. Cytoskeleton (Hoboken) 76(9-10):449-456 PMID:31614074
Perez AM and Thorner J (2019) Septin-associated proteins Aim44 and Nis1 traffic between the bud neck and the nucleus in the yeast Saccharomyces cerevisiae. Cytoskeleton (Hoboken) 76(1):15-32 PMID:30341817
Emmerstorfer-Augustin A, et al. (2018) Tracking yeast pheromone receptor Ste2 endocytosis using fluorogen-activating protein tagging. Mol Biol Cell 29(22):2720-2736 PMID:30207829
Leskoske KL, et al. (2018) Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2. Genes Dev 32(23-24):1576-1590 PMID:30478248
Roelants FM, et al. (2018) TOR complex 2-regulated protein kinase Ypk1 controls sterol distribution by inhibiting StARkin domain-containing proteins located at plasma membrane-endoplasmic reticulum contact sites. Mol Biol Cell 29(17):2128-2136 PMID:29927351
Roelants FM, et al. (2017) TOR Complex 2-Regulated Protein Kinase Fpk1 Stimulates Endocytosis via Inhibition of Ark1/Prk1-Related Protein Kinase Akl1 in Saccharomyces cerevisiae. Mol Cell Biol 37(7) PMID:28069741
Alvaro CG, et al. (2016) Differential Phosphorylation Provides a Switch to Control How α-Arrestin Rod1 Down-regulates Mating Pheromone Response in Saccharomyces cerevisiae. Genetics 203(1):299-317 PMID:26920760
Finnigan GC and Thorner J (2016) mCAL: A New Approach for Versatile Multiplex Action of Cas9 Using One sgRNA and Loci Flanked by a Programmed Target Sequence. G3 (Bethesda) 6(7):2147-56 PMID:27185399
Finnigan GC, et al. (2016) Detection of protein-protein interactions at the septin collar in Saccharomyces cerevisiae using a tripartite split-GFP system. Mol Biol Cell 27(17):2708-25 PMID:27385335
Finnigan GC, et al. (2016) Coordinate action of distinct sequence elements localizes checkpoint kinase Hsl1 to the septin collar at the bud neck in Saccharomyces cerevisiae. Mol Biol Cell 27(14):2213-33 PMID:27193302
Guerreiro JF, et al. (2016) Sphingolipid biosynthesis upregulation by TOR complex 2-Ypk1 signaling during yeast adaptive response to acetic acid stress. Biochem J 473(23):4311-4325 PMID:27671892
Booth EA, et al. (2015) A Förster Resonance Energy Transfer (FRET)-based System Provides Insight into the Ordered Assembly of Yeast Septin Hetero-octamers. J Biol Chem 290(47):28388-28401 PMID:26416886
Finnigan GC and Thorner J (2015) Complex in vivo Ligation Using Homologous Recombination and High-efficiency Plasmid Rescue from Saccharomyces cerevisiae. Bio Protoc 5(13) PMID:26523287
Finnigan GC, et al. (2015) The Carboxy-Terminal Tails of Septins Cdc11 and Shs1 Recruit Myosin-II Binding Factor Bni5 to the Bud Neck in Saccharomyces cerevisiae. Genetics 200(3):843-62 PMID:25971666
Johnson CR, et al. (2015) Cytosolic chaperones mediate quality control of higher-order septin assembly in budding yeast. Mol Biol Cell 26(7):1323-44 PMID:25673805
O'Donnell AF, et al. (2015) 2-Deoxyglucose impairs Saccharomyces cerevisiae growth by stimulating Snf1-regulated and α-arrestin-mediated trafficking of hexose transporters 1 and 3. Mol Cell Biol 35(6):939-55 PMID:25547292
Prosser DC, et al. (2015) α-Arrestins participate in cargo selection for both clathrin-independent and clathrin-mediated endocytosis. J Cell Sci 128(22):4220-34 PMID:26459639
Sartorel E, et al. (2015) Plasma membrane aminoglycerolipid flippase function is required for signaling competence in the yeast mating pheromone response pathway. Mol Biol Cell 26(1):134-50 PMID:25378585
Muir A, et al. (2014) TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids. Elife 3 PMID:25279700
O'Donnell AF, et al. (2013) A calcineurin-dependent switch controls the trafficking function of α-arrestin Aly1/Art6. J Biol Chem 288(33):24063-80 PMID:23824189
de Val N, et al. (2013) Native cysteine residues are dispensable for the structure and function of all five yeast mitotic septins. Proteins 81(11):1964-79 PMID:23775754
Bertin A, et al. (2012) Three-dimensional ultrastructure of the septin filament network in Saccharomyces cerevisiae. Mol Biol Cell 23(3):423-32 PMID:22160597
Lee YJ, et al. (2012) Reciprocal phosphorylation of yeast glycerol-3-phosphate dehydrogenases in adaptation to distinct types of stress. Mol Cell Biol 32(22):4705-17 PMID:22988299
Roelants FM, et al. (2011) Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(48):19222-7 PMID:22080611
Chen RE and Thorner J (2010) Systematic epistasis analysis of the contributions of protein kinase A- and mitogen-activated protein kinase-dependent signaling to nutrient limitation-evoked responses in the yeast Saccharomyces cerevisiae. Genetics 185(3):855-70 PMID:20421603
Chen RE, et al. (2010) Dynamic localization of Fus3 mitogen-activated protein kinase is necessary to evoke appropriate responses and avoid cytotoxic effects. Mol Cell Biol 30(17):4293-307 PMID:20584989
Garrenton LS, et al. (2010) Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling. Proc Natl Acad Sci U S A 107(26):11805-10 PMID:20547860
Patterson JC, et al. (2010) Single-cell analysis reveals that insulation maintains signaling specificity between two yeast MAPK pathways with common components. Sci Signal 3(144):ra75 PMID:20959523
Roelants FM, et al. (2010) A protein kinase network regulates the function of aminophospholipid flippases. Proc Natl Acad Sci U S A 107(1):34-9 PMID:19966303
Garrenton LS, et al. (2009) Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence. Mol Cell Biol 29(2):582-601 PMID:19001089
McMurray MA and Thorner J (2009) Reuse, replace, recycle. Specificity in subunit inheritance and assembly of higher-order septin structures during mitotic and meiotic division in budding yeast. Cell Cycle 8(2):195-203 PMID:19164941
Bertin A, et al. (2008) Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly. Proc Natl Acad Sci U S A 105(24):8274-9 PMID:18550837
McMurray MA and Thorner J (2008) Septin stability and recycling during dynamic structural transitions in cell division and development. Curr Biol 18(16):1203-8 PMID:18701287
Westfall PJ, et al. (2008) Stress resistance and signal fidelity independent of nuclear MAPK function. Proc Natl Acad Sci U S A 105(34):12212-7 PMID:18719124
Chen RE and Thorner J (2007) Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1773(8):1311-40 PMID:17604854
Schüller C, et al. (2007) Membrane-active compounds activate the transcription factors Pdr1 and Pdr3 connecting pleiotropic drug resistance and membrane lipid homeostasis in saccharomyces cerevisiae. Mol Biol Cell 18(12):4932-44 PMID:17881724
Strahl T and Thorner J (2007) Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae. Biochim Biophys Acta 1771(3):353-404 PMID:17382260
Asano S, et al. (2006) Direct phosphorylation and activation of a Nim1-related kinase Gin4 by Elm1 in budding yeast. J Biol Chem 281(37):27090-8 PMID:16861226
Truckses DM, et al. (2006) The RA domain of Ste50 adaptor protein is required for delivery of Ste11 to the plasma membrane in the filamentous growth signaling pathway of the yeast Saccharomyces cerevisiae. Mol Cell Biol 26(3):912-28 PMID:16428446
Weirich CS, et al. (2006) Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export. Nat Cell Biol 8(7):668-76 PMID:16783364
Westfall PJ and Thorner J (2006) Analysis of mitogen-activated protein kinase signaling specificity in response to hyperosmotic stress: use of an analog-sensitive HOG1 allele. Eukaryot Cell 5(8):1215-28 PMID:16896207
Strahl T, et al. (2005) Yeast phosphatidylinositol 4-kinase, Pik1, has essential roles at the Golgi and in the nucleus. J Cell Biol 171(6):967-79 PMID:16365163
Roelants FM, et al. (2004) Differential roles of PDK1- and PDK2-phosphorylation sites in the yeast AGC kinases Ypk1, Pkc1 and Sch9. Microbiology (Reading) 150(Pt 10):3289-304 PMID:15470109
Rudge SA, et al. (2004) Roles of phosphoinositides and of Spo14p (phospholipase D)-generated phosphatidic acid during yeast sporulation. Mol Biol Cell 15(1):207-18 PMID:14528019
Versele M and Thorner J (2004) Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4. J Cell Biol 164(5):701-15 PMID:14993234
Strahl T, et al. (2003) Conservation of regulatory function in calcium-binding proteins: human frequenin (neuronal calcium sensor-1) associates productively with yeast phosphatidylinositol 4-kinase isoform, Pik1. J Biol Chem 278(49):49589-99 PMID:14512421
Wang Y, et al. (2003) Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex. J Biol Chem 278(25):22284-9 PMID:12668671
Roelants FM, et al. (2002) Pkh1 and Pkh2 differentially phosphorylate and activate Ypk1 and Ykr2 and define protein kinase modules required for maintenance of cell wall integrity. Mol Biol Cell 13(9):3005-28 PMID:12221112
Adamkewicz JI, et al. (2001) High affinity interaction of yeast transcriptional regulator, Mot1, with TATA box-binding protein (TBP). J Biol Chem 276(15):11883-94 PMID:11278722
Bardwell AJ, et al. (2001) A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission. J Biol Chem 276(13):10374-86 PMID:11134045
Cid VJ, et al. (2001) Dynamic localization of the Swe1 regulator Hsl7 during the Saccharomyces cerevisiae cell cycle. Mol Biol Cell 12(6):1645-69 PMID:11408575
Künzler M, et al. (2001) Mutations in the YRB1 gene encoding yeast ran-binding-protein-1 that impair nucleocytoplasmic transport and suppress yeast mating defects. Genetics 157(3):1089-105 PMID:11238397
Adamkewicz JI, et al. (2000) Purification and enzymic properties of Mot1 ATPase, a regulator of basal transcription in the yeast Saccharomyces cerevisiae. J Biol Chem 275(28):21158-68 PMID:10887203
Ames JB, et al. (2000) Structure and calcium-binding properties of Frq1, a novel calcium sensor in the yeast Saccharomyces cerevisiae. Biochemistry 39(40):12149-61 PMID:11015193
Sette C, et al. (2000) Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein. Mol Biol Cell 11(11):4033-49 PMID:11071925
Hama H, et al. (1999) Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae. J Biol Chem 274(48):34294-300 PMID:10567405
Hendricks KB, et al. (1999) Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase. Nat Cell Biol 1(4):234-41 PMID:10559922
Shulewitz MJ, et al. (1999) Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 19(10):7123-37 PMID:10490648
Bardwell L, et al. (1998) Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. Proc Natl Acad Sci U S A 95(26):15400-5 PMID:9860980
Bardwell L, et al. (1998) Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK. Genes Dev 12(18):2887-98 PMID:9744865
Flick JS and Thorner J (1998) An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae. Genetics 148(1):33-47 PMID:9475719
Stolz LE, et al. (1998) Identification and characterization of an essential family of inositol polyphosphate 5-phosphatases (INP51, INP52 and INP53 gene products) in the yeast Saccharomyces cerevisiae. Genetics 148(4):1715-29 PMID:9560389
Brazill DT, et al. (1997) Mck1, a member of the glycogen synthase kinase 3 family of protein kinases, is a negative regulator of pyruvate kinase in the yeast Saccharomyces cerevisiae. J Bacteriol 179(13):4415-8 PMID:9209064
Cook JG, et al. (1997) Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway. Nature 390(6655):85-8 PMID:9363895
David NE, et al. (1997) Expression and purification of the Saccharomyces cerevisiae alpha-factor receptor (Ste2p), a 7-transmembrane-segment G protein-coupled receptor. J Biol Chem 272(24):15553-61 PMID:9182592
Inouye C, et al. (1997) Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: application of a differential interaction trap assay for examining protein-protein interactions. Genetics 147(2):479-92 PMID:9335587
Wilson LK, et al. (1997) Casein kinase II catalyzes tyrosine phosphorylation of the yeast nucleolar immunophilin Fpr3. J Biol Chem 272(20):12961-7 PMID:9148902
Bardwell L, et al. (1996) Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7. Mol Cell Biol 16(7):3637-50 PMID:8668180
Cook JG, et al. (1996) Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes Dev 10(22):2831-48 PMID:8918885
Dohlman HG, et al. (1996) Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). Mol Cell Biol 16(9):5194-209 PMID:8756677
Melcher ML and Thorner J (1996) Identification and characterization of the CLK1 gene product, a novel CaM kinase-like protein kinase from the yeast Saccharomyces cerevisiae. J Biol Chem 271(47):29958-68 PMID:8939941
Swartzman EE, et al. (1996) The PAL1 gene product is a peroxisomal ATP-binding cassette transporter in the yeast Saccharomyces cerevisiae. J Cell Biol 132(4):549-63 PMID:8647887
Harris E, et al. (1995) Gain-of-function mutations in a human calmodulin-like protein identify residues critical for calmodulin action in yeast. Mol Gen Genet 247(2):137-47 PMID:7753022
Jiang W, et al. (1995) Overexpression of the yeast MCK1 protein kinase suppresses conditional mutations in centromere-binding protein genes CBF2 and CBF5. Mol Gen Genet 246(3):360-6 PMID:7854321
Ma D, et al. (1995) Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway. Mol Biol Cell 6(7):889-909 PMID:7579701
Wilson LK, et al. (1995) The yeast immunophilin Fpr3 is a physiological substrate of the tyrosine-specific phosphoprotein phosphatase Ptp1. J Biol Chem 270(42):25185-93 PMID:7559654
Auble DT, et al. (1994) Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism. Genes Dev 8(16):1920-34 PMID:7958867
Bardwell L, et al. (1994) Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae. Dev Biol 166(2):363-79 PMID:7813763
Benton BM, et al. (1994) A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus. J Cell Biol 127(3):623-39 PMID:7525596
Florio M, et al. (1994) Aberrant protein phosphorylation at tyrosine is responsible for the growth-inhibitory action of pp60v-src expressed in the yeast Saccharomyces cerevisiae. Mol Biol Cell 5(3):283-96 PMID:8049521
Harris E, et al. (1994) Functional consequences in yeast of single-residue alterations in a consensus calmodulin. J Cell Sci 107 ( Pt 11):3235-49 PMID:7699020
Hasson MS, et al. (1994) Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway. Mol Cell Biol 14(2):1054-65 PMID:8289786
Salama SR, et al. (1994) G1 cyclin degradation: the PEST motif of yeast Cln2 is necessary, but not sufficient, for rapid protein turnover. Mol Cell Biol 14(12):7953-66 PMID:7969135
Dohlman HG, et al. (1993) Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 90(20):9688-92 PMID:8415763
Flanagan CA, et al. (1993) Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability. Science 262(5138):1444-8 PMID:8248783
Flick JS and Thorner J (1993) Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiae. Mol Cell Biol 13(9):5861-76 PMID:8395015
Gimble FS and Thorner J (1993) Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae. J Biol Chem 268(29):21844-53 PMID:8408039
Kuchler K, et al. (1993) The a-factor transporter (STE6 gene product) and cell polarity in the yeast Saccharomyces cerevisiae. J Cell Biol 120(5):1203-15 PMID:7679674
Lim MY, et al. (1993) Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine. J Biol Chem 268(28):21155-64 PMID:8407952
Bremer MC, et al. (1992) VDE endonuclease cleaves Saccharomyces cerevisiae genomic DNA at a single site: physical mapping of the VMA1 gene. Nucleic Acids Res 20(20):5484 PMID:1437572
Cyert MS and Thorner J (1992) Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone. Mol Cell Biol 12(8):3460-9 PMID:1321337
Davis JL, et al. (1992) A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol 12(4):1879-92 PMID:1312673
Flanagan CA and Thorner J (1992) Purification and characterization of a soluble phosphatidylinositol 4-kinase from the yeast Saccharomyces cerevisiae. J Biol Chem 267(33):24117-25 PMID:1331109
Gimble FS and Thorner J (1992) Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae. Nature 357(6376):301-6 PMID:1534148
Kuchler K and Thorner J (1992) Functional expression of human mdr1 in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 89(6):2302-6 PMID:1347948
Kuchler K, et al. (1992) Dedicated transporters for peptide export and intercompartmental traffic in the yeast Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol 57:579-92 PMID:1339696
Cyert MS, et al. (1991) Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase. Proc Natl Acad Sci U S A 88(16):7376-80 PMID:1651503
Fields FO and Thorner J (1991) Genetic suppression analysis of the function of a protein kinase C (PKC1 gene product) in Saccharomyces cerevisiae cell cycle progression: the SKCd mutations. Cold Spring Harb Symp Quant Biol 56:51-60 PMID:1819504
Blumer KJ and Thorner J (1990) Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling. Proc Natl Acad Sci U S A 87(11):4363-7 PMID:2161538
Bresnahan PA, et al. (1990) Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo. J Cell Biol 111(6 Pt 2):2851-9 PMID:2269657
Dailey D, et al. (1990) Novel yeast protein kinase (YPK1 gene product) is a 40-kilodalton phosphotyrosyl protein associated with protein-tyrosine kinase activity. Mol Cell Biol 10(12):6244-56 PMID:1701015
Courchesne WE, et al. (1989) A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae. Cell 58(6):1107-19 PMID:2673544
Davis TN and Thorner J (1989) Vertebrate and yeast calmodulin, despite significant sequence divergence, are functionally interchangeable. Proc Natl Acad Sci U S A 86(20):7909-13 PMID:2554295
Flessel MC, et al. (1989) The MF alpha 1 gene of Saccharomyces cerevisiae: genetic mapping and mutational analysis of promoter elements. Genetics 121(2):223-36 PMID:2659433
Fuller RS, et al. (1989) Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease. Proc Natl Acad Sci U S A 86(5):1434-8 PMID:2646633
Fuller RS, et al. (1989) Intracellular targeting and structural conservation of a prohormone-processing endoprotease. Science 246(4929):482-6 PMID:2683070
Kuchler K, et al. (1989) Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells. EMBO J 8(13):3973-84 PMID:2686977
Schafer WR, et al. (1989) Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans. Science 245(4916):379-85 PMID:2569235
Blumer KJ, et al. (1988) The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae. J Biol Chem 263(22):10836-42 PMID:2839507
Blumer KJ, et al. (1988) Functional domains of a peptide hormone receptor: the alpha-factor receptor (STE2 gene product) of the yeast Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol 53 Pt 2:591-603 PMID:2855497
Thomas G, et al. (1988) Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells. Science 241(4862):226-30 PMID:3291117
Kunisawa R, et al. (1987) Complete nucleotide sequence of the gene encoding the regulatory subunit of 3',5'-cyclic AMP-dependent protein kinase from the yeast Saccharomyces cerevisiae. Nucleic Acids Res 15(1):368-9 PMID:3547325
Whiteway M, et al. (1987) The yeast ARD1 gene product is required for repression of cryptic mating-type information at the HML locus. Mol Cell Biol 7(10):3713-22 PMID:3316986
Julius D, et al. (1984) Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor. Cell 37(3):1075-89 PMID:6430565
Stetler GL and Thorner J (1984) Molecular cloning of hormone-responsive genes from the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 81(4):1144-8 PMID:6366798
Brake AJ, et al. (1983) A functional prepro-alpha-factor gene in Saccharomyces yeasts can contain three, four, or five repeats of the mature pheromone sequence. Mol Cell Biol 3(8):1440-50 PMID:6353204
Emr SD, et al. (1983) An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast. Proc Natl Acad Sci U S A 80(23):7080-4 PMID:6359161
Julius D, et al. (1983) Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase. Cell 32(3):839-52 PMID:6339075
Sprague GF, et al. (1983) Cell interactions and regulation of cell type in the yeast Saccharomyces cerevisiae. Annu Rev Microbiol 37:623-60 PMID:6357062
Bisson LF and Thorner J (1982) Effect of halogenated pyrimidine 5'-mononucleotides on dTMP-permeable yeast strains and the isolation and characterization of resistant mutants. Mol Gen Genet 186(4):467-74 PMID:6752656
Bisson LF and Thorner J (1982) Mutations in the pho80 gene confer permeability to 5'-mononucleotides in Saccharomyces cerevisiae. Genetics 102(3):341-59 PMID:6293915
Ciejek E and Thorner J (1979) Recovery of S. cerevisiae a cells from G1 arrest by alpha factor pheromone requires endopeptidase action. Cell 18(3):623-35 PMID:391400
Bisson L and Thorner J (1977) Thymidine 5'-monophosphate-requiring mutants of Saccharomyces cerevisiae are deficient in thymidylate synthetase. J Bacteriol 132(1):44-50 PMID:334734