HML / HML Overview
- Standard Name
- Systematic Name
- SGD ID
- Feature Type
Mating type cassette - left; unexpressed complete copy of the mating-type genes, silenced by the Sir2 histone deacetylase and its associated SIR1, SIR3 and SIR4 proteins; mating-type switching involves replacement of the Ya or Yalpha sequences present at the MAT locus with either the a or alpha genes located at one of the HM loci in a process stimulated by the HO endonuclease; sequence replacement occurs by gene conversion, leaving the donor unaltered
- Comparative Info
Integrated model organism details available at the Alliance of Genome Resources website
The S. cerevisiae Reference Genome sequence is derived from laboratory strain
S288C. Download DNA or protein sequence, view genomic context and
coordinates. Click "Sequence Details" to view all sequence information for this locus, including that
for other strains.
A summary of the locus, written by SGD Biocurators following a thorough review of the literature. Links
to gene names and curated GO terms are included within the Summary Paragraphs.
All manually curated literature for the specified gene, organized into topics according to their
relevance to the gene (Primary Literature, Additional Literature, or Review). Click "Literature Details"
to view all literature information for this locus, including shared literature between genes.