Tollervey D and Parker R (2022) Christine Guthrie: Splicing genetics and mentorship into the RNA world. Proc Natl Acad Sci U S A 119(47):e2216884119 PMID:36343216
Van Treeck B, et al. (2018) RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome. Proc Natl Acad Sci U S A 115(11):2734-2739 PMID:29483269
Khong A, et al. (2017) The Stress Granule Transcriptome Reveals Principles of mRNA Accumulation in Stress Granules. Mol Cell 68(4):808-820.e5 PMID:29129640
Rao BS and Parker R (2017) Numerous interactions act redundantly to assemble a tunable size of P bodies in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 114(45):E9569-E9578 PMID:29078371
Eshleman N, et al. (2016) Defects in THO/TREX-2 function cause accumulation of novel cytoplasmic mRNP granules that can be cleared by autophagy. RNA 22(8):1200-14 PMID:27251550
Garcia JF and Parker R (2016) Ubiquitous accumulation of 3' mRNA decay fragments in Saccharomyces cerevisiae mRNAs with chromosomally integrated MS2 arrays. RNA 22(5):657-9 PMID:27090788
Mitchell SF and Parker R (2016) Identification of Endogenous mRNA-Binding Proteins in Yeast Using Crosslinking and PolyA Enrichment. Methods Mol Biol 1421:153-63 PMID:26965264
Garcia JF and Parker R (2015) MS2 coat proteins bound to yeast mRNAs block 5' to 3' degradation and trap mRNA decay products: implications for the localization of mRNAs by MS2-MCP system. RNA 21(8):1393-5 PMID:26092944
Mitchell SF and Parker R (2015) In vivo cross-linking followed by polyA enrichment to identify yeast mRNA binding proteins. Methods Mol Biol 1259:35-47 PMID:25579578
Walters RW, et al. (2015) Differential effects of Ydj1 and Sis1 on Hsp70-mediated clearance of stress granules in Saccharomyces cerevisiae. RNA 21(9):1660-71 PMID:26199455
Shukla S and Parker R (2014) Quality control of assembly-defective U1 snRNAs by decapping and 5'-to-3' exonucleolytic digestion. Proc Natl Acad Sci U S A 111(32):E3277-86 PMID:25071210
Walters RW, et al. (2014) Edc3 function in yeast and mammals is modulated by interaction with NAD-related compounds. G3 (Bethesda) 4(4):613-22 PMID:24504254
Harigaya Y and Parker R (2012) Global analysis of mRNA decay intermediates in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 109(29):11764-9 PMID:22752303
Rajyaguru P, et al. (2012) Scd6 targets eIF4G to repress translation: RGG motif proteins as a class of eIF4G-binding proteins. Mol Cell 45(2):244-54 PMID:22284680
Hilliker A, et al. (2011) The DEAD-box protein Ded1 modulates translation by the formation and resolution of an eIF4F-mRNA complex. Mol Cell 43(6):962-72 PMID:21925384
Swisher KD and Parker R (2011) Interactions between Upf1 and the decapping factors Edc3 and Pat1 in Saccharomyces cerevisiae. PLoS One 6(10):e26547 PMID:22065998
Harigaya Y, et al. (2010) Identification and analysis of the interaction between Edc3 and Dcp2 in Saccharomyces cerevisiae. Mol Cell Biol 30(6):1446-56 PMID:20086104
Swisher KD and Parker R (2010) Localization to, and effects of Pbp1, Pbp4, Lsm12, Dhh1, and Pab1 on stress granules in Saccharomyces cerevisiae. PLoS One 5(4):e10006 PMID:20368989
Luhtala N and Parker R (2009) LSM1 over-expression in Saccharomyces cerevisiae depletes U6 snRNA levels. Nucleic Acids Res 37(16):5529-36 PMID:19596813
Thompson DM and Parker R (2009) The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae. J Cell Biol 185(1):43-50 PMID:19332891
Pedro-Segura E, et al. (2008) The Cth2 ARE-binding protein recruits the Dhh1 helicase to promote the decay of succinate dehydrogenase SDH4 mRNA in response to iron deficiency. J Biol Chem 283(42):28527-35 PMID:18715869
Pilkington GR and Parker R (2008) Pat1 contains distinct functional domains that promote P-body assembly and activation of decapping. Mol Cell Biol 28(4):1298-312 PMID:18086885
Brengues M and Parker R (2007) Accumulation of polyadenylated mRNA, Pab1p, eIF4E, and eIF4G with P-bodies in Saccharomyces cerevisiae. Mol Biol Cell 18(7):2592-602 PMID:17475768
Decker CJ, et al. (2007) Edc3p and a glutamine/asparagine-rich domain of Lsm4p function in processing body assembly in Saccharomyces cerevisiae. J Cell Biol 179(3):437-49 PMID:17984320
Baker KE and Parker R (2006) Conventional 3' end formation is not required for NMD substrate recognition in Saccharomyces cerevisiae. RNA 12(8):1441-5 PMID:16809819
Beliakova-Bethell N, et al. (2006) Virus-like particles of the Ty3 retrotransposon assemble in association with P-body components. RNA 12(1):94-101 PMID:16373495
Hilgers V, et al. (2006) Translation-independent inhibition of mRNA deadenylation during stress in Saccharomyces cerevisiae. RNA 12(10):1835-45 PMID:16940550
Muhlrad D and Parker R (2005) The yeast EDC1 mRNA undergoes deadenylation-independent decapping stimulated by Not2p, Not4p, and Not5p. EMBO J 24(5):1033-45 PMID:15706350
Tharun S, et al. (2005) Mutations in the Saccharomyces cerevisiae LSM1 gene that affect mRNA decapping and 3' end protection. Genetics 170(1):33-46 PMID:15716506
Wilson MA, et al. (2005) Genetic interactions between [PSI+] and nonstop mRNA decay affect phenotypic variation. Proc Natl Acad Sci U S A 102(29):10244-9 PMID:16002465
Cheng Z, et al. (2004) Crystal structure of Ski8p, a WD-repeat protein with dual roles in mRNA metabolism and meiotic recombination. Protein Sci 13(10):2673-84 PMID:15340168
Kshirsagar M and Parker R (2004) Identification of Edc3p as an enhancer of mRNA decapping in Saccharomyces cerevisiae. Genetics 166(2):729-39 PMID:15020463
Schwartz D, et al. (2003) The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme. RNA 9(2):239-51 PMID:12554867
Tucker M, et al. (2002) Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae. EMBO J 21(6):1427-36 PMID:11889048
Coller JM, et al. (2001) The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes. RNA 7(12):1717-27 PMID:11780629
Dunckley T, et al. (2001) Two related proteins, Edc1p and Edc2p, stimulate mRNA decapping in Saccharomyces cerevisiae. Genetics 157(1):27-37 PMID:11139489
He W and Parker R (2001) The yeast cytoplasmic LsmI/Pat1p complex protects mRNA 3' termini from partial degradation. Genetics 158(4):1445-55 PMID:11514438
Hilleren P and Parker R (2001) Defects in the mRNA export factors Rat7p, Gle1p, Mex67p, and Rat8p cause hyperadenylation during 3'-end formation of nascent transcripts. RNA 7(5):753-64 PMID:11350039
Tharun S and Parker R (2001) Targeting an mRNA for decapping: displacement of translation factors and association of the Lsm1p-7p complex on deadenylated yeast mRNAs. Mol Cell 8(5):1075-83 PMID:11741542
Tucker M, et al. (2001) The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae. Cell 104(3):377-86 PMID:11239395
Jacobs Anderson JS and Parker R (2000) Computational identification of cis-acting elements affecting post-transcriptional control of gene expression in Saccharomyces cerevisiae. Nucleic Acids Res 28(7):1604-17 PMID:10710427
Schwartz DC and Parker R (2000) mRNA decapping in yeast requires dissociation of the cap binding protein, eukaryotic translation initiation factor 4E. Mol Cell Biol 20(21):7933-42 PMID:11027264
van Hoof A, et al. (2000) Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast. EMBO J 19(6):1357-65 PMID:10716935
van Hoof A, et al. (2000) Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs. Mol Cell Biol 20(2):441-52 PMID:10611222
Dunckley T and Parker R (1999) The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif. EMBO J 18(19):5411-22 PMID:10508173
Hilleren P and Parker R (1999) mRNA surveillance in eukaryotes: kinetic proofreading of proper translation termination as assessed by mRNP domain organization? RNA 5(6):711-9 PMID:10376871
LaGrandeur T and Parker R (1999) The cis acting sequences responsible for the differential decay of the unstable MFA2 and stable PGK1 transcripts in yeast include the context of the translational start codon. RNA 5(3):420-33 PMID:10094310
Muhlrad D and Parker R (1999) Recognition of yeast mRNAs as "nonsense containing" leads to both inhibition of mRNA translation and mRNA degradation: implications for the control of mRNA decapping. Mol Biol Cell 10(11):3971-8 PMID:10564284
Muhlrad D and Parker R (1999) Aberrant mRNAs with extended 3' UTRs are substrates for rapid degradation by mRNA surveillance. RNA 5(10):1299-307 PMID:10573121
Schwartz DC and Parker R (1999) Mutations in translation initiation factors lead to increased rates of deadenylation and decapping of mRNAs in Saccharomyces cerevisiae. Mol Cell Biol 19(8):5247-56 PMID:10409716
Olivas WM, et al. (1997) Analysis of the yeast genome: identification of new non-coding and small ORF-containing RNAs. Nucleic Acids Res 25(22):4619-25 PMID:9358174
Beelman CA, et al. (1996) An essential component of the decapping enzyme required for normal rates of mRNA turnover. Nature 382(6592):642-6 PMID:8757137
Caponigro G and Parker R (1995) Multiple functions for the poly(A)-binding protein in mRNA decapping and deadenylation in yeast. Genes Dev 9(19):2421-32 PMID:7557393
Mandart E and Parker R (1995) Effects of mutations in the Saccharomyces cerevisiae RNA14, RNA15, and PAP1 genes on polyadenylation in vivo. Mol Cell Biol 15(12):6979-86 PMID:8524265
Beelman CA and Parker R (1994) Differential effects of translational inhibition in cis and in trans on the decay of the unstable yeast MFA2 mRNA. J Biol Chem 269(13):9687-92 PMID:8144558
Muhlrad D, et al. (1994) Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript. Genes Dev 8(7):855-66 PMID:7926773
Caponigro G, et al. (1993) A small segment of the MAT alpha 1 transcript promotes mRNA decay in Saccharomyces cerevisiae: a stimulatory role for rare codons. Mol Cell Biol 13(9):5141-8 PMID:8355674
Decker CJ and Parker R (1993) A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation. Genes Dev 7(8):1632-43 PMID:8393418
Parker R and Siliciano PG (1993) Evidence for an essential non-Watson-Crick interaction between the first and last nucleotides of a nuclear pre-mRNA intron. Nature 361(6413):660-2 PMID:8437627
Heaton B, et al. (1992) Analysis of chimeric mRNAs derived from the STE3 mRNA identifies multiple regions within yeast mRNAs that modulate mRNA decay. Nucleic Acids Res 20(20):5365-73 PMID:1437553
Herrick D, et al. (1990) Identification and comparison of stable and unstable mRNAs in Saccharomyces cerevisiae. Mol Cell Biol 10(5):2269-84 PMID:2183028
Parker R and Jacobson A (1990) Translation and a 42-nucleotide segment within the coding region of the mRNA encoded by the MAT alpha 1 gene are involved in promoting rapid mRNA decay in yeast. Proc Natl Acad Sci U S A 87(7):2780-4 PMID:2181450
Parker R (1989) Genetic methods for identification and characterization of RNA-RNA and RNA-protein interactions. Methods Enzymol 180:510-7 PMID:2482431
Ruohola H, et al. (1988) Orientation-dependent function of a short CYC1 DNA fragment in directing mRNA 3' end formation in yeast. Proc Natl Acad Sci U S A 85(14):5041-5 PMID:2839828
Parker R, et al. (1987) Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA. Cell 49(2):229-39 PMID:3552247
Vijayraghavan U, et al. (1986) Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome. EMBO J 5(7):1683-95 PMID:3017708
Parker R and Guthrie C (1985) A point mutation in the conserved hexanucleotide at a yeast 5' splice junction uncouples recognition, cleavage, and ligation. Cell 41(1):107-18 PMID:2986840