Bravo-Alonso I, et al. (2023) Pathogenic variants of the coenzyme A biosynthesis-associated enzyme phosphopantothenoylcysteine decarboxylase cause autosomal-recessive dilated cardiomyopathy. J Inherit Metab Dis 46(2):261-272 PMID:36564894
Zekhnini A, et al. (2023) The ENA1 Na+-ATPase Gene Is Regulated by the SPS Sensing Pathway and the Stp1/Stp2 Transcription Factors. Int J Mol Sci 24(6) PMID:36982620
Albacar M, et al. (2022) The toxic effects of yeast Ppz1 phosphatase are counteracted by subcellular relocalization mediated by its regulatory subunit Hal3. FEBS Lett 596(12):1556-1566 PMID:35278214
Casamayor A, et al. (2022) Comparative Analysis of Type 1 and Type Z Protein Phosphatases Reveals D615 as a Key Residue for Ppz1 Regulation. Int J Mol Sci 23(3) PMID:35163251
Santolaria C, et al. (2022) Functional mapping of the N-terminal region of the yeast moonlighting protein Sis2/Hal3 reveals crucial residues for Ppz1 regulation. FEBS J 289(23):7500-7518 PMID:35811492
Albacar M, et al. (2021) The Toxic Effects of Ppz1 Overexpression Involve Nha1-Mediated Deregulation of K+ and H+ Homeostasis. J Fungi (Basel) 7(12) PMID:34946993
Zhang C, et al. (2019) Characterization of the atypical Ppz/Hal3 phosphatase system from the pathogenic fungus Cryptococcus neoformans. Mol Microbiol 111(4):898-917 PMID:30536975
Zhang C, et al. (2019) Protein Phosphatase Ppz1 Is Not Regulated by a Hal3-Like Protein in Plant Pathogen Ustilago maydis. Int J Mol Sci 20(15) PMID:31387236
Santolaria C, et al. (2018) Mutations at the hydrophobic core affect Hal3 trimer stability, reducing its Ppz1 inhibitory capacity but not its PPCDC moonlighting function. Sci Rep 8(1):14701 PMID:30279472
Bru S, et al. (2016) Polyphosphate is involved in cell cycle progression and genomic stability in Saccharomyces cerevisiae. Mol Microbiol 101(3):367-80 PMID:27072996
Petrezsélyová S, et al. (2016) Regulation of the Na+/K+-ATPase Ena1 Expression by Calcineurin/Crz1 under High pH Stress: A Quantitative Study. PLoS One 11(6):e0158424 PMID:27362362
Petrényi K, et al. (2016) Analysis of Two Putative Candida albicans Phosphopantothenoylcysteine Decarboxylase / Protein Phosphatase Z Regulatory Subunits Reveals an Unexpected Distribution of Functional Roles. PLoS One 11(8):e0160965 PMID:27504636
Pérez-Sampietro M, et al. (2016) The yeast Aft2 transcription factor determines selenite toxicity by controlling the low affinity phosphate transport system. Sci Rep 6:32836 PMID:27618952
Tatjer L, et al. (2016) The Saccharomyces cerevisiae Ptc1 protein phosphatase attenuates G2-M cell cycle blockage caused by activation of the cell wall integrity pathway. Mol Microbiol 101(4):671-87 PMID:27169355
Tatjer L, et al. (2016) Wide-Ranging Effects of the Yeast Ptc1 Protein Phosphatase Acting Through the MAPK Kinase Mkk1. Genetics 202(1):141-56 PMID:26546002
Abrie JA, et al. (2015) Complex stability and dynamic subunit interchange modulates the disparate activities of the yeast moonlighting proteins Hal3 and Vhs3. Sci Rep 5:15774 PMID:26514574
Canadell D, et al. (2015) Functional interactions between potassium and phosphate homeostasis in Saccharomyces cerevisiae. Mol Microbiol 95(3):555-72 PMID:25425491
Canadell D, et al. (2015) Impact of high pH stress on yeast gene expression: A comprehensive analysis of mRNA turnover during stress responses. Biochim Biophys Acta 1849(6):653-64 PMID:25900709
Fernández-Niño M, et al. (2015) The Cytosolic pH of Individual Saccharomyces cerevisiae Cells Is a Key Factor in Acetic Acid Tolerance. Appl Environ Microbiol 81(22):7813-21 PMID:26341199
Ariño J, et al. (2014) Systems biology of monovalent cation homeostasis in yeast: the translucent contribution. Adv Microb Physiol 64:1-63 PMID:24797924
Serra-Cardona A, et al. (2014) Coregulated expression of the Na+/phosphate Pho89 transporter and Ena1 Na+-ATPase allows their functional coupling under high-pH stress. Mol Cell Biol 34(24):4420-35 PMID:25266663
González A, et al. (2013) Ptc6 is required for proper rapamycin-induced down-regulation of the genes coding for ribosomal and rRNA processing proteins in S. cerevisiae. PLoS One 8(5):e64470 PMID:23704987
González A, et al. (2013) Molecular analysis of a conditional hal3 vhs3 yeast mutant links potassium homeostasis with flocculation and invasiveness. Fungal Genet Biol 53:1-9 PMID:23454581
Casamayor A, et al. (2012) The role of the Snf1 kinase in the adaptive response of Saccharomyces cerevisiae to alkaline pH stress. Biochem J 444(1):39-49 PMID:22372618
Gelis S, et al. (2012) Adaptation to potassium starvation of wild-type and K(+)-transport mutant (trk1,2) of Saccharomyces cerevisiae: 2-dimensional gel electrophoresis-based proteomic approach. Microbiologyopen 1(2):182-93 PMID:22950024
Kahm M, et al. (2012) Potassium starvation in yeast: mechanisms of homeostasis revealed by mathematical modeling. PLoS Comput Biol 8(6):e1002548 PMID:22737060
Marquina M, et al. (2012) Lack of the Glc7 phosphatase regulatory subunit Ypi1 activates the morphogenetic checkpoint. Int J Biochem Cell Biol 44(11):1862-71 PMID:22750472
Prescott TA, et al. (2012) Inhibition of human calcineurin and yeast calcineurin-dependent gene expression by Jasminum humile leaf and root extracts. J Ethnopharmacol 140(2):293-7 PMID:22301445
Ádám C, et al. (2012) Protein phosphatase CaPpz1 is involved in cation homeostasis, cell wall integrity and virulence of Candida albicans. Microbiology (Reading) 158(Pt 5):1258-1267 PMID:22343349
Barreto L, et al. (2011) A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae. Eukaryot Cell 10(9):1241-50 PMID:21724935
Casado C, et al. (2010) Regulation of Trk-dependent potassium transport by the calcineurin pathway involves the Hal5 kinase. FEBS Lett 584(11):2415-20 PMID:20412803
Ferrer-Dalmau J, et al. (2010) Ref2, a regulatory subunit of the yeast protein phosphatase 1, is a novel component of cation homoeostasis. Biochem J 426(3):355-64 PMID:20028335
Navarrete C, et al. (2010) Lack of main K+ uptake systems in Saccharomyces cerevisiae cells affects yeast performance in both potassium-sufficient and potassium-limiting conditions. FEMS Yeast Res 10(5):508-17 PMID:20491939
Pérez-Valle J, et al. (2010) Hal4 and Hal5 protein kinases are required for general control of carbon and nitrogen uptake and metabolism. Eukaryot Cell 9(12):1881-90 PMID:20952580
Gaillard H, et al. (2009) Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair. PLoS Genet 5(2):e1000364 PMID:19197357
González A, et al. (2009) Normal function of the yeast TOR pathway requires the type 2C protein phosphatase Ptc1. Mol Cell Biol 29(10):2876-88 PMID:19273591
Ruiz A, et al. (2009) Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis. Nat Chem Biol 5(12):920-8 PMID:19915539
González A, et al. (2008) Use of the TRP1 auxotrophic marker for gene disruption and phenotypic analysis in yeast: a note of warning. FEMS Yeast Res 8(1):2-5 PMID:17892472
Ruiz A, et al. (2008) Direct regulation of genes involved in glucose utilization by the calcium/calcineurin pathway. J Biol Chem 283(20):13923-33 PMID:18362157
Aksenova A, et al. (2007) The HAL3-PPZ1 dependent regulation of nonsense suppression efficiency in yeast and its influence on manifestation of the yeast prion-like determinant [ISP(+)]. Genes Cells 12(4):435-45 PMID:17397392
Pagani MA, et al. (2007) Disruption of iron homeostasis in Saccharomyces cerevisiae by high zinc levels: a genome-wide study. Mol Microbiol 65(2):521-37 PMID:17630978
Pedelini L, et al. (2007) YPI1 and SDS22 proteins regulate the nuclear localization and function of yeast type 1 phosphatase Glc7. J Biol Chem 282(5):3282-92 PMID:17142459
García-Salcedo R, et al. (2006) Heterologous expression implicates a GATA factor in regulation of nitrogen metabolic genes and ion homeostasis in the halotolerant yeast Debaryomyces hansenii. Eukaryot Cell 5(8):1388-98 PMID:16896222
González A, et al. (2006) Transcriptional profiling of the protein phosphatase 2C family in yeast provides insights into the unique functional roles of Ptc1. J Biol Chem 281(46):35057-69 PMID:16973600
Platara M, et al. (2006) The transcriptional response of the yeast Na(+)-ATPase ENA1 gene to alkaline stress involves three main signaling pathways. J Biol Chem 281(48):36632-42 PMID:17023428
Ruiz A, et al. (2006) Role of protein phosphatases 2C on tolerance to lithium toxicity in the yeast Saccharomyces cerevisiae. Mol Microbiol 62(1):263-77 PMID:16956380
Serrano R, et al. (2006) Signaling alkaline pH stress in the yeast Saccharomyces cerevisiae through the Wsc1 cell surface sensor and the Slt2 MAPK pathway. J Biol Chem 281(52):39785-95 PMID:17088254
Alberola TM, et al. (2004) A new set of DNA macrochips for the yeast Saccharomyces cerevisiae: features and uses. Int Microbiol 7(3):199-206 PMID:15492934
Muñoz I, et al. (2004) Functional characterization of the yeast Ppz1 phosphatase inhibitory subunit Hal3: a mutagenesis study. J Biol Chem 279(41):42619-27 PMID:15292171
Ruiz A, et al. (2004) Functional characterization of the Saccharomyces cerevisiae VHS3 gene: a regulatory subunit of the Ppz1 protein phosphatase with novel, phosphatase-unrelated functions. J Biol Chem 279(33):34421-30 PMID:15192104
Serrano R, et al. (2004) Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. J Biol Chem 279(19):19698-704 PMID:14993228
Viladevall L, et al. (2004) Characterization of the calcium-mediated response to alkaline stress in Saccharomyces cerevisiae. J Biol Chem 279(42):43614-24 PMID:15299026
Ariño J and Herrero E (2003) Use of tetracycline-regulatable promoters for functional analysis of protein phosphatases in yeast. Methods Enzymol 366:347-58 PMID:14674260
García-Gimeno MA, et al. (2003) Molecular characterization of Ypi1, a novel Saccharomyces cerevisiae type 1 protein phosphatase inhibitor. J Biol Chem 278(48):47744-52 PMID:14506263
Muñoz I, et al. (2003) Identification of multicopy suppressors of cell cycle arrest at the G1-S transition in Saccharomyces cerevisiae. Yeast 20(2):157-69 PMID:12518319
Ruiz A, et al. (2003) Regulation of ENA1 Na(+)-ATPase gene expression by the Ppz1 protein phosphatase is mediated by the calcineurin pathway. Eukaryot Cell 2(5):937-48 PMID:14555476
Simón E, et al. (2003) Mutagenesis analysis of the yeast Nha1 Na+/H+ antiporter carboxy-terminal tail reveals residues required for function in cell cycle. FEBS Lett 545(2-3):239-45 PMID:12804783
Serrano R, et al. (2002) The transcriptional response to alkaline pH in Saccharomyces cerevisiae: evidence for calcium-mediated signalling. Mol Microbiol 46(5):1319-33 PMID:12453218
Yenush L, et al. (2002) The Ppz protein phosphatases are key regulators of K+ and pH homeostasis: implications for salt tolerance, cell wall integrity and cell cycle progression. EMBO J 21(5):920-9 PMID:11867520
Proft M, et al. (2001) Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress. EMBO J 20(5):1123-33 PMID:11230135
Simón E, et al. (2001) A screening for high copy suppressors of the sit4 hal3 synthetically lethal phenotype reveals a role for the yeast Nha1 antiporter in cell cycle regulation. J Biol Chem 276(32):29740-7 PMID:11382758
Vissi E, et al. (2001) Functional analysis of the Neurospora crassa PZL-1 protein phosphatase by expression in budding and fission yeast. Yeast 18(2):115-24 PMID:11169754
de Nadal E, et al. (2001) A role for the Ppz Ser/Thr protein phosphatases in the regulation of translation elongation factor 1Balpha. J Biol Chem 276(18):14829-34 PMID:11278758
Bilsland-Marchesan E, et al. (2000) Rck2 kinase is a substrate for the osmotic stress-activated mitogen-activated protein kinase Hog1. Mol Cell Biol 20(11):3887-95 PMID:10805732
Clotet J, et al. (1999) The yeast ser/thr phosphatases sit4 and ppz1 play opposite roles in regulation of the cell cycle. Mol Cell Biol 19(3):2408-15 PMID:10022927
Hajji K, et al. (1999) Disruption and phenotypic analysis of seven ORFs from the left arm of chromosome XV of Saccharomyces cerevisiae. Yeast 15(5):435-41 PMID:10220002
de Nadal E, et al. (1999) Biochemical and genetic analyses of the role of yeast casein kinase 2 in salt tolerance. J Bacteriol 181(20):6456-62 PMID:10515937
Thomson TM, et al. (1998) Role of UEV-1A, a homologue of the tumor suppressor protein TSG101, in protection from DNA damage. FEBS Lett 423(1):49-52 PMID:9580084
de Nadal E, et al. (1998) The yeast halotolerance determinant Hal3p is an inhibitory subunit of the Ppz1p Ser/Thr protein phosphatase. Proc Natl Acad Sci U S A 95(13):7357-62 PMID:9636153
Balcells L, et al. (1997) Regulation of salt tolerance in fission yeast by a protein-phosphatase-Z-like Ser/Thr protein phosphatase. Eur J Biochem 250(2):476-83 PMID:9428701
Aldea M, et al. (1996) Sequence analysis of a 12 801 bp fragment of the left arm of yeast chromosome XV containing a putative 6-phosphofructo-2-kinase gene, a gene for a possible glycophospholipid-anchored surface protein and six other open reading frames. Yeast 12(10B Suppl):1053-8 PMID:8896270
Casamayor A, et al. (1996) Sequence analysis of a 13.4 kbp fragment from the left arm of chromosome XV reveals a malate dehydrogenase gene, a putative Ser/Thr protein kinase, the ribosomal L25 gene and four new open reading frames. Yeast 12(10B Suppl):1013-20 PMID:8896265
Clotet J, et al. (1996) The NH2-terminal extension of protein phosphatase PPZ1 has an essential functional role. J Biol Chem 271(42):26349-55 PMID:8824289
Gamo FJ, et al. (1996) Analysis of the DNA sequence of a 15,500 bp fragment near the left telomere of chromosome XV from Saccharomyces cerevisiae reveals a putative sugar transporter, a carboxypeptidase homologue and two new open reading frames. Yeast 12(7):709-14 PMID:8810044
Casamayor A, et al. (1995) DNA sequence analysis of a 13 kbp fragment of the left arm of yeast chromosome XV containing seven new open reading frames. Yeast 11(13):1281-8 PMID:8553699
Casas C, et al. (1995) Sequence analysis of a 9873 bp fragment of the left arm of yeast chromosome XV that contains the ARG8 and CDC33 genes, a putative riboflavin synthase beta chain gene, and four new open reading frames. Yeast 11(11):1061-7 PMID:7502581
Posas F, et al. (1995) Biochemical characterization of recombinant yeast PPZ1, a protein phosphatase involved in salt tolerance. FEBS Lett 368(1):39-44 PMID:7615085
Posas F, et al. (1995) The PPZ protein phosphatases are important determinants of salt tolerance in yeast cells. J Biol Chem 270(22):13036-41 PMID:7768897
Posas F, et al. (1993) The PPZ protein phosphatases are involved in the maintenance of osmotic stability of yeast cells. FEBS Lett 318(3):282-6 PMID:8382634
Posas F, et al. (1993) The gene PPG encodes a novel yeast protein phosphatase involved in glycogen accumulation. J Biol Chem 268(2):1349-54 PMID:7678255
Corominas J, et al. (1992) Glycogen metabolism in a Saccharomyces cerevisiae phosphoglucose isomerase (pgil) disruption mutant. FEBS Lett 310(2):182-6 PMID:1397270
Posas F, et al. (1992) Molecular cloning and analysis of a yeast protein phosphatase with an unusual amino-terminal region. J Biol Chem 267(17):11734-40 PMID:1318299
Clotet J, et al. (1991) The gene DIS2S1 is essential in Saccharomyces cerevisiae and is involved in glycogen phosphorylase activation. Curr Genet 19(5):339-42 PMID:1913873
Fernández-Bañares I, et al. (1991) Glycogen hyperaccumulation in Saccharomyces cerevisiae ras2 mutant. A biochemical study. FEBS Lett 290(1-2):38-42 PMID:1655535