Primary Literature
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- Vlahakis A, et al. (2017) Stress-response transcription factors Msn2 and Msn4 couple TORC2-Ypk1 signaling and mitochondrial respiration to ATG8 gene expression and autophagy. Autophagy 13(11):1804-1812 PMID: 29198169
- Baretić D, et al. (2016) Tor forms a dimer through an N-terminal helical solenoid with a complex topology. Nat Commun 7:11016 PMID: 27072897
- Guerreiro JF, et al. (2016) Sphingolipid biosynthesis upregulation by TOR complex 2-Ypk1 signaling during yeast adaptive response to acetic acid stress. Biochem J 473(23):4311-4325 PMID: 27671892
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- Vlahakis A, et al. (2016) Calcium channel regulator Mid1 links TORC2-mediated changes in mitochondrial respiration to autophagy. J Cell Biol 215(6):779-788 PMID: 27899413
- Weisman R (2016) Target of Rapamycin (TOR) Regulates Growth in Response to Nutritional Signals. Microbiol Spectr 4(5) PMID: 27763256
- Yerlikaya S, et al. (2016) TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae. Mol Biol Cell 27(2):397-409 PMID: 26582391
- Bartlett K, et al. (2015) TORC2 and eisosomes are spatially interdependent, requiring optimal level of phosphatidylinositol 4, 5-bisphosphate for their integrity. J Biosci 40(2):299-311 PMID: 25963258
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- Kennedy MA, et al. (2014) A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast. PLoS Genet 10(1):e1004010 PMID: 24465216
- Muir A, et al. (2014) TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids. Elife 3 PMID: 25279700
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- Niles BJ, et al. (2014) TOR complex 2-Ypk1 signaling maintains sphingolipid homeostasis by sensing and regulating ROS accumulation. Cell Rep 6(3):541-52 PMID: 24462291
- Vlahakis A and Powers T (2014) A role for TOR complex 2 signaling in promoting autophagy. Autophagy 10(11):2085-6 PMID: 25426890
- Vlahakis A, et al. (2014) TOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagy. Proc Natl Acad Sci U S A 111(29):10586-91 PMID: 25002487
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