New & Noteworthy
November 09, 2021
Would you like to see the shape of your protein?
SGD now contains links to AlphaFold in the Resources section of the Summary, Protein and Homology pages for every gene.
- The links through SGD give quick access to EMBL–European Bioinformatics Institute‘s new, highly accurate tool for predicting protein structure.
- Given a peptide sequence for an uncharacterized protein, AlphaFold will model predicted domains and provide relative confidence levels for each portion of the prediction.
- The predicted domains can then be compared to known protein structures (using a tool such as PDBeFold to seek matches to characterized protein families).
- Whether or not a family is identified, the comparison will yield clues to protein function to help design the next experiments.