New & Noteworthy

Call for Yeast Genetics Meeting 2018 Award Nominations!

July 25, 2017


The Yeast Genetics Meeting will be held August 22-26, 2018 at Stanford University.

You are invited to submit nominations to the meeting organizers for the awards and presentations that have become a cornerstone of the meeting.

  • The Lifetime Achievement Award is given for lifetime contributions in the field of yeast genetics and outstanding community service.
  • The Ira Herskowitz Award is given for outstanding contributions in the field of yeast research in the last 20 years. This award is usually given to scientists under 50.
  • The Winge-Lindegren Address is a thought-provoking perspective given by a leader in the field of yeast genetics.
  • The Lee Hartwell Lecture is given by a noted researcher in the field who has used yeast in a way that has had an obvious impact on other fields.

Previous awardees are listed on last year’s Yeast Genetics Meeting award site.
 
The deadline for nominations is Tuesday, August 1, 2017. Nominations should include: name, affiliation, email address, and a one or two sentence overview of why you are proposing the individual. Please send nominations to mahoney@genetics-gsa.org.

Categories: Announcements

Exploring the Global Yeast Genetic Interaction Network

April 17, 2017


Global yeast genetic interaction profile similarity network. Image from TheCellMap.org.

With the construction of a global genetic interaction network in S. cerevisiae, it’s not hard to see why yeast genetic interactions remain a treasure trove for biological discovery. When combined with tools for visualization and analysis, these data can be used to draw powerful functional maps of the cell and infer potential functions for uncharacterized genes.

In a recent paper published in G3: Genes|Genomes|Genetics, Usaj et al. describe a web-based resource for exploring the global yeast genetic interaction network: TheCellMap.org. TheCellMap.org is an online database and visualization tool for quantitative yeast genetic interaction data. It provides an interactive version of the global yeast genetic interaction similarity network described by Costanzo et al., enabling users to scroll through and zoom in on different clusters of functionally related genes within the network. Users can search for specific genes or alleles, extract and re-organize sub-networks for genes of interest, functionally annotate genetic interactions, and more. Further, if more details about a gene are needed, users can even double-click on the gene to be taken to its respective locus summary page at SGD!

For more information about this resource, see http://TheCellMap.org/about/ or access the publication at https://doi.org/10.1534/g3.117.040220.

Categories: Announcements

Apply Now for the 2017 Yeast Genetics & Genomics Course

March 17, 2017


For almost 50 years, the legendary Yeast Genetics & Genomics course has been taught each summer at Cold Spring Harbor Laboratory.

For almost 50 years, the legendary Yeast Genetics & Genomics course has been taught each summer at Cold Spring Harbor Laboratory. (OK, the name didn’t include “Genomics” in the beginning…). The list of people who have taken the course reads like a Who’s Who of yeast research, including Nobel laureates and many of today’s leading scientists.

The application deadline is April 15th, so don’t miss your chance! Find all the details and application form here.

This year’s instructors – Grant Brown, Maitreya Dunham, and Elçin Ünal – have designed a course (July 25 – August 14) that provides a comprehensive education in all things yeast, from classical genetics through up-to-the-minute genomics. Students will perform and interpret experiments, learning about things like:

  • How to Find and Analyze Yeast Information Using SGD
  • Isolation and Characterization of Mutants
  • Transformation of Plasmids & Integrating DNAs
  • Meiosis & Tetrad Dissection as well as mitotic recombination
  • Synthetic Genetic Array Analysis
  • Next-Gen. whole-genome and multiplexed DNA barcode sequencing
  • Genome-based methods of analysis
  • Visualization of yeast using light and fluorescence microscopy
  • Exploring synthetic biology with CRISPR/CAS9-directed engineering of biosynthetic pathways

Techniques have been summarized in a completely updated course manual, which was recently published by CSHL Press.

legendary plate race

There’s fierce competition between students at CSHL courses in the Plate Race, a relay in which teams carry stacks of 40 Petri dishes (used, of course).

Scientists who aren’t part of large, well-known yeast labs are especially encouraged to apply – for example, professors and instructors who want to incorporate yeast into their undergraduate genetics classrooms; scientists who want to transition from mathematical, computational, or engineering disciplines into bench science; and researchers from small labs or institutions where it would otherwise be difficult to learn the fundamentals of yeast genetics and genomics. Significant stipends (in the 30-50% range of total fees) are available to individuals expressing a need for financial support and who are selected into the course.

Besides its scientific content, the fun and camaraderie at the course is also legendary. In between all the hard work there are late-night chats at the bar and swimming at the beach. There’s a fierce competition between students at the various CSHL courses in the Plate Race, which is a relay in which teams have to carry stacks of 40 Petri dishes (used, of course). There’s also a sailboat trip, a microscopy contest, and a mysterious “Dr. Evil” lab!

The Yeast Genetics & Genomics Course is loads of fun – don’t miss out!

Categories: Announcements

Don’t miss Fungal Pathogen Genomics!

January 30, 2017


The application deadline for the Fungal Pathogen Genomics workshop to be held May 11-17, 2017 at the Wellcome Genome Campus in Hinxton, Cambridge, UK is fast approaching! Be sure to apply by this Friday, February 3!

This exciting new week-long course aims to provide experimental biologists working on fungal organisms with hands-on experience in genomic-scale data analysis; including genome browsers and comparison tools, data mining using resources such as FungiDB, Ensembl/PhytoPathDB, PomBase, SGD/CGD, MycoCosm, analysis of genome annotation, and next generation sequence analysis and visualization (including RNA sequence analysis and variant calling). An important aim is that the participants should understand the origin of data available in public resources and how to analyse it in conjunction with their own.

The course is taught as a collaborative effort between available fungal informatics resources. The majority of this intensive course will be based on hands-on exercises, supplemented by lectures on genomics and bioinformatics techniques and keynote presentations by distinguished guest speakers.

Don’t miss out – apply now!

Categories: Announcements

Happy Holidays from SGD!

December 20, 2016


Happy Holidays from SGD!

We want to take this opportunity to wish you and your family, friends and lab mates the best during the upcoming holidays.

Stanford University will be closed for two weeks from Wednesday, December 21, 2016 through Tuesday, January 3, 2017. Regular operations will resume on Wednesday, January 4, 2017.

Although SGD staff members will be taking time off, please rest assured that the website will remain up and running throughout the winter break, and we will attempt to keep connected via email should you have any questions.

Happy Holidays and best wishes for all good things in the coming New Year!

Categories: Announcements

Sign Up Now! Next SGD Webinar: December 14, 2016

December 12, 2016


Looking for human disease-related information in SGD? There is so much to find! Active areas of curation at SGD include yeast-human homology, disease associations, alleles and phenotype variants, and functional complementation relationships.

Join our upcoming webinar on December 14th, 9:30 AM PST to learn about homology and disease data in SGD. In this quick 15 minute session, we will demonstrate the best ways to research this information on our website and provide a helpful tutorial on related SGD tools and features. Our webinars are always an excellent opportunity to connect with the SGD team–be sure to bring questions if you have them!

All are welcome to this event. If you are interested attending, please register herehttp://bit.ly/SGDwebinar6

This is the sixth episode in the SGD Webinar Series. For more information on the SGD Webinar Series, please visit our wiki page: SGD Webinar Series.

Categories: Announcements Homologs Yeast and Human Disease Tutorial

New SGD Help Video: Finding Human Homology & Disease Information

October 24, 2016


Looking for human disease-related information in SGD? There is so much to find! Active areas of curation at SGD include yeast-human homology, alleles and phenotype variants, functional complementation relationships, and disease associations. There are plenty of ways to find this information on our website, and it takes just 90 seconds to learn how – what are you waiting for?

For more SGD Help Videos, visit our YouTube channel, and be sure to subscribe so you don’t miss anything!

Categories: Announcements Homologs Yeast and Human Disease Tutorial

Sign Up Now for the Next SGD Webinar: September 7, 2016

September 02, 2016


The SPELL expression analysis tool at SGD makes it easy to find expression datasets and coexpressed genes that are relevant to your genes of interest. Just plug in a set of genes and go! Once given a query, SGD’s instance of SPELL locates informative expression datasets from over 270 published studies and identifies additional genes with similar expression profiles.

Find out how to use SPELL in our upcoming webinar on September 7th, 9:30 AM PDT. This quick 10-minute tutorial will explain how to run a multi-gene query in SPELL, locate expression datasets relevant to your query, and find genes with similar expression profiles.

If you are interested in attending this event, please register using this online form: http://bit.ly/SGDwebinar5

This is the fifth episode in the SGD Webinar Series. For more information on the SGD Webinar Series, please visit our wiki page: SGD Webinar Series.

Categories: Announcements Tutorial

SGD: New Search, New Style

August 22, 2016


SGD is pleased to introduce our new faceted search, replete with new features that make navigating SGD easier than ever. It’s simple to get started – just click on the “Try this?” button on the SGD homepage. Try a search for your favorite gene or your favorite topic of study in our improved search box! We have also introduced a sleek new look that retains the same familiar features and menus, but is now optimized for mobile use.
 
New features of the search include:
  • Superior search box functionality: New autocomplete options connect to information faster than ever
  • Sorting options: Results sorted alphabetically, by relevance, and by number of annotations
  • Download gene lists: Export gene lists from search results into a text file with the “Wrapped” and “Download” options
  • Faceted searching: Narrow search results by using categories like Genes, Molecular Functions, Phenotypes, and more!
To get familiar with the new search, check out this quick help video to get started:
 

As you explore SGD’s new and improved search, please be sure to send us any feedback via email or through this short survey.
 

Categories: Announcements Website changes

Coming Soon – New Search and New Styling

August 15, 2016


SGD is planning to release a new faceted search on Monday, August 22, 2016, along with some new site styling optimized for mobile use. The refactored search has been available for the last few months on our beta site: sgd-beta.stanford.edu.

New features of the search include:

  • an expanded selection of fields included in the autocomplete list
  • the ability to enter the SGD site and explore data and pages without an initial query – just click the Explore button and go!
  • narrowing of search results by categories such as genes, molecular functions, and phenotypes (and more!)

Navigating SGD will soon be easier than ever. Please explore the new search, try some different queries, view the new styling on your favorite pages, and send us your feedback via email, or through this short survey.

Categories: Announcements Website changes

Sign Up Now for the Next SGD Webinar: August 3, 2016

July 28, 2016


SGD’s Variant Viewer is an easy-to-learn web application that allows visualization of differences in both gene and protein sequences. With Variant Viewer, you can compare the nucleotide and amino acid sequences of your favorite genes in twelve widely-used S. cerevisiae strains. Our upcoming webinar on August 3rd, 9:30 AM PDT will provide a quick 10 minute tutorial on how to use Variant Viewer. We will demonstrate how to compare nucleotide and amino acid sequences of different S. cerevisiae genomes, and how to visualize strain-specific single nucleotide polymorphisms, insertions, and deletions contained within a given open reading frame.

If you are interested in attending this event, please register using this online form: http://bit.ly/SGDwebinar4

This is the fourth episode in the SGD Webinar Series. For more information on the SGD Webinar Series, please visit our wiki page: SGD Webinar Series.

Categories: Announcements Tutorial Sequence

Alliance of Genome Resources – Survey

July 21, 2016


An Alliance of Genome Resources has been formed to provide better support for the biological sciences.

Please help the Alliance by completing the short survey at: http://bit.ly/SGD-AllianceSurvey

Six of the founding members of the Alliance of Genome Resources (Saccharomyces Genome Database, WormBase, FlyBase, ZFIN, MGI, and the Gene Ontology Consortium) attended the GSA’s The Allied Genetics Conference in Orlando from July 13-17. It was a great opportunity for staff of each of these individual resources to talk about their new collaboration to integrate their content and software into a single resource that benefits biologists, educators, and clinicians alike.

The model organism databases all have a long history of reaching out to their respective communities for feedback on new developments and input on future directions. Carrying on this tradition, the Alliance has created a short survey to obtain feedback on how best to provide human disease information in relation to model organisms. In addition, the Alliance is asking for input on the prioritization of website visualizations, tools, and curation of specific data types.

We appreciate your continued support!

Categories: Announcements

Look for SGD at TAGC 2016!

July 05, 2016


SGD staff will be attending The Allied Genetics Conference 2016 (TAGC) on July 13-17, 2016, in Orlando, Florida. We will be hosting a Workshop, Posters, and an Exhibit Booth. We’ll be available during the entire conference to hear your comments or suggestions about SGD and answer your questions.

Five different model organism databases – SGD, WormBase, FlyBase, MGI, and ZFIN – will also be doing open demonstrations and tutorials in the Demo Room (Palms Ballroom Canary 3-4). There will be scheduled group presentations, one-on-one tutorials, troubleshooting and discussions.

Follow @yeastgenome and #TAGC16 on Twitter for the latest research being presented at TAGC.

Workshop: “Getting Even More out of SGD”

Saturday, July 16, 4:00pm – 6:00pm, Crystal Ballroom G2

We’ll be discussing our curation efforts in capturing yeast-human functional complementation data, the new sequence Variant Viewer, new genome browser, new data in YeastMine, and more. Bring your questions and comments – we love feedback!

Exhibit Booth

SGD will also have an exhibit booth at the conference, in conjunction with WormBase and FlyBase! Come by booth #530 (right across from the GSA booth) to take a spin on our site, learn about various features of the databases, and provide us with feedback as to what we can do to improve your SGD experience. You might even receive a prize for a good question or suggestion!

…and Psst! Be sure to ask about the newly-formed Alliance of Genome Resources

Posters

In addition to the Workshop, SGD staff will present five posters – please stop by and chat with us.

Poster no. Title Presenter Location Time/Day
Y3076/A The Saccharomyces Genome Database Variant Viewer Olivia Lang Cypress Ballroom 1:30pm – 2:30pm, Thursday, 7/14
Y3168/C Saccharomyces Genome Database: How to find what you are looking for Gail Binkley Cypress Ballroom 1:30pm – 2:30pm, Thursday, 7/14
Y3170/B Saccharomyces Genome Database: Outreach and online training services Kevin MacPherson Cypress Ballroom 1:30pm – 2:30pm, Thursday, 7/14
Y3191/B Integrating Post-Translational Modification Data into the Saccharomyces Genome Database Sage Hellerstedt Cypress Ballroom 2:30pm – 3:30pm, Thursday, 7/14
Y3157/A Homology curation at SGD: budding yeast as a model for eukaryotic biology Stacia Engel Cypress Ballroom 2:30pm – 3:30pm, Thursday, 7/14

Demo Room

SGD, WormBase, FlyBase, MGI, and ZFIN invite all Conference registrants to come to the Demo Room (Palms Ballroom Canary 3-4) to learn how to make the best use of MOD tools and features for your research and teaching.

All day on Thursday 7/14 and Friday 7/15, other than during scheduled group presentations from 12:45pm – 1:30pm and 6:15pm – 7:30pm, personnel are available in the demo room for one-on-one tutorials, troubleshooting and discussions. Make sure you don’t miss the SGD Demo Room presentations on Thursday 7/14 from 6:15pm – 6:30pm and Friday from 12:45pm – 1:00pm!

Find these SGD staff members at the conference:


Mike Cherry
Stacia Engel
Stacia Engel
Pedro Assis
Pedro Assis
Gail Binkley
Gail Binkley
Sage Hellerstedt
Sage Hellerstedt
Kalpana Karra
Kalpana Karra
Olivia Lang
Olivia Lang
Kevin MacPherson
Kevin MacPherson

Categories: Announcements Conferences

Support Model Organism Databases!

June 22, 2016


Model Organisms such as yeast, worm, fly, fish, and mouse are key drivers of biological research, providing experimental systems that yield insights into human biology and health. Model Organism Databases (MODs) enable researchers all over the world to uncover basic, conserved biological mechanisms relevant to new medical therapies. These discoveries have been recognized by many Nobel Prizes over the last decades.

NHGRI/NIH has recently advanced a plan in which the MODs will be integrated into a single combined database, along with a 30% reduction in funding for each MOD (see also these Nature and Science news stories). While integration presents advantages, the funding cut will cripple core functions such as high quality literature curation and genome annotation, degrading the utility of the MODs.

Leaders of several Model Organism communities, working with the Genetics Society of America (GSA), have come together to write a Statement of Support for the MODs, and to urge the NIH to revise its proposal. We ask all scientists who value the community-specific nature of the MODs to sign this ‘open letter’. The letter, along with all signatures, will be presented to NIH Director Francis Collins at a GSA-organized meeting on July 14, 2016 during The Allied Genetics Conference in Orlando. We urge you to add your name, and to spread the word to all researchers who value the MODs.

In other words, sign this letter!

Categories: Announcements Yeast and Human Disease News and Views

Next SGD Webinar: June 1, 2016

May 26, 2016


If you’re not already using JBrowse to view all your favorite S. cerevisiae genes…you should be! SGD’s JBrowse is a quick and easy way to browse through the information-rich yeast genome. Using JBrowse, you can visualize spatial relationships between genes, locate SGD annotations throughout the yeast genome, and align chromosomal features to hundreds of experimental data sets.

Our upcoming webinar on June 1st will provide a short 15-minute tutorial on the basics of JBrowse. We will demonstrate how to navigate the genome with JBrowse, locate your favorite genes or chromosomal features, and visualize experimental data with data tracks. Whether you’re an experienced GBrowse user looking to try JBrowse for the first time, or someone new to genome browsing as a whole, this webinar is sure to help you get started.

If you are interested in attending this event, please register using this online form: http://bit.ly/SGDwebinar3

This is the third episode of the SGD Webinar Series. For more information on the SGD Webinar Series, please visit our wiki page: SGD Webinar Series.

Categories: Announcements Tutorial

Sign Up Now for the Next SGD Webinar: May 4th, 2016

April 26, 2016


If you’re not already using YeastMine to answer all your questions about S. cerevisiae genes and gene products…you should be! SGD’s YeastMine is a powerful search tool that can retrieve, compare, and analyze data on thousands of genes at a time, greatly reducing the time needed to answer real, practical research questions. Through YeastMine, questions such as “What proportion of plasma membrane proteins are essential?” or “How many different gene products physically interact with the mitochondrial ribosome?” can be answered within minutes.

Next week on May 4th, 2016 at 9:30 AM PDT, we will provide a brief webinar tutorial on how to run queries and create gene lists in SGD’s YeastMine. As a practical demonstration of YeastMine, we will also showcase a research scenario in which yeast-human homology data is used to predict potential chemotherapy targets for human cancers.

Space for this webinar is limited. To reserve your spot, please register for the event using this online form: http://bit.ly/registerFor2ndSGDwebinar

This is the second episode of the SGD Webinar Series. If you missed the first one, or if you’d like to find out more about upcoming webinars, please visit our wiki page: SGD Webinar Series.

Categories: Announcements Yeast and Human Disease

Apply Now for the 2016 Yeast Genetics & Genomics Course

March 30, 2016


For almost 50 years, the legendary Yeast Genetics & Genomics course has been taught each summer at Cold Spring Harbor Laboratory.

For almost 50 years, the legendary Yeast Genetics & Genomics course has been taught each summer at Cold Spring Harbor Laboratory. (OK, the name didn’t include “Genomics” in the beginning…). The list of people who have taken the course reads like a Who’s Who of yeast research, including Nobel laureates and many of today’s leading scientists.

The application deadline is April 15th, so don’t miss your chance! Find all the details and application form here.

This year’s instructors – Grant Brown, Maitreya Dunham, and Marc Gartenberg – have designed a course (July 26 – August 15) that provides a comprehensive education in all things yeast, from classical genetics through up-to-the-minute genomics. Students will perform and interpret experiments, learning about things like:

  • How to Find and Analyze Yeast Information Using SGD
  • Isolation and Characterization of Mutants
  • Transformation of Plasmids & Integrating DNAs
  • Meiosis & Tetrad Dissection as well as mitotic recombination
  • Synthetic Genetic Array Analysis
  • Next-Gen. whole-genome and multiplexed DNA barcode sequencing
  • Genome-based methods of analysis
  • Visualization of yeast using light and fluorescence microscopy
  • Exploring synthetic biology with CRISPR/CAS9-directed engineering of biosynthetic pathways

Techniques have been summarized in a completely updated course manual, which was recently published by CSHL Press.

legendary plate race

There’s fierce competition between students at CSHL courses in the Plate Race, a relay in which teams carry stacks of 40 Petri dishes (used, of course).

Scientists who aren’t part of large, well-known yeast labs are especially encouraged to apply – for example, professors and instructors who want to incorporate yeast into their undergraduate genetics classrooms; scientists who want to transition from mathematical, computational, or engineering disciplines into bench science; and researchers from small labs or institutions where it would otherwise be difficult to learn the fundamentals of yeast genetics and genomics. Significant stipends (in the 30-50% range of total fees) are available to individuals expressing a need for financial support and who are selected into the course.

Besides its scientific content, the fun and camaraderie at the course is also legendary. In between all the hard work there are late-night chats at the bar and swimming at the beach. There’s a fierce competition between students at the various CSHL courses in the Plate Race, which is a relay in which teams have to carry stacks of 40 Petri dishes (used, of course). There’s also a sailboat trip, a microscopy contest, and a mysterious “Dr. Evil” lab!

Last year’s Yeast Genetics & Genomics Course was loads of fun – don’t miss out!

Categories: Announcements

Join SGD at The Allied Genetics Conference

January 12, 2016


TAGC 2016 imageSGD will be attending The Allied Genetics Conference (TAGC) in Orlando, Florida, July 13–17, 2016! For the first time ever, the meetings of the yeast, C. elegans, ciliate, Drosophila, mouse, and zebrafish model organism communities will be united under one roof, along with a new meeting on population, evolutionary, and quantitative genetics.

Submit your abstracts now! Abstract submission will be open until March 23, 2016. If you want GREAT science and access to the leaders of the field, then TAGC is the place for you. SGD will be there, will you?

Categories: Announcements Conferences

Happy Holidays from SGD

December 17, 2015

We want to take this opportunity to wish you and your family, friends and lab mates the best during the upcoming holidays. Stanford University will be closed for two weeks starting at 5:00 p.m. PST on December 18th, reopening on January 4th, 2016. Although SGD staff members will be taking time off, please rest assured that the website will remain up and running throughout the winter break, and we will attempt to keep connected via email should you have any questions.

Categories: Announcements

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