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FHL1 / YPR104C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
SPP42 2 18
Feature Type
ORF , Verified
Description
Regulator of ribosomal protein (RP) transcription; has forkhead associated domain that binds phosphorylated proteins; recruits coactivator Ifh1p or corepressor Crf1p to RP gene promoters; also has forkhead DNA-binding domain though in vitro DNA binding assays give inconsistent results; computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p motifs at others; suppresses RNA pol III and splicing factor prp4 mutants 1 2 3 4 5 6 7 8

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