Sequence Help

HSP82 / YPL240C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
HSP90 34
Protein Product
Hsp90 family chaperone HSP82
Feature Type
ORF , Verified
Description
Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; promotes solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication; human homolog, HSP90AB1, complements null mutant 3 4 5 6 7 8 9 11 12 13 14
Paralog
HSC82 13

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