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ESA1 / YOR244W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
TAS1 , KAT5 8
Protein Product
NuA4 histone acetyltransferase complex catalytic subunit ESA1
Feature Type
ORF , Verified
Description
Catalytic subunit of the histone acetyltransferase complex (NuA4); acetylates four conserved internal lysines of histone H4 N-terminal tail and can acetylate histone H2A; master regulator of cellular acetylation balance; required for cell cycle progression and transcriptional silencing at the rDNA locus and regulation of autophagy; human ortholog TIP60/KAT5 is implicated in cancer and other diseases, functionally complements lethality of the esa1 null mutation 1 2 3 4 5 6 7
EC Number
2.3.1.48

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