ESA1 / YOR244W Homology


Standard Name
ESA1 1
Systematic Name
YOR244W
SGD ID
SGD:S000005770
Aliases
TAS1 , KAT5 8
Feature Type
ORF , Verified
Description
Catalytic subunit of the histone acetyltransferase complex (NuA4); acetylates four conserved internal lysines of histone H4 N-terminal tail and can acetylate histone H2A; master regulator of cellular acetylation balance; required for cell cycle progression and transcriptional silencing at the rDNA locus and regulation of autophagy; human ortholog TIP60/KAT5 is implicated in cancer and other diseases, functionally complements lethality of the esa1 null mutation 1 2 3 4 5 6 7
Comparative Info

Homologs

Homology calls are sourced from the Alliance of Genome Resources. Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. The Alliance provides the results of all methods that have been benchmarked by the Quest for Orthologs Consortium (QfO). The homolog inferences from the different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT), which integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, and ZFIN.


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Species Gene ID Gene name Source

Functional Complementation

Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD).

1 entry for 1 complement


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SpeciesGene IDStrain backgroundDirectionDetailsSourceReference
Homo sapiensHGNC:5275S288Cother complements yeastHuman gene allows growth of the yeast haploid null mutant after sporulation of a heterozygous diploid.SGDKachroo AH, et al. (2015)
PMID:25999509
Showing 1 to 1 of 1 entries

Fungal Homologs

Fungal Homology calls are sourced from AllianceMine, which compiles fungal homology calls from FungiDB, CGD, Panther, PomBase, TreeFam, HomoloGene, and SGD.


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Species Gene ID Gene name Description Source

External Identifiers

List of external identifiers for the protein from various database sources.

45 entries for 12 sources


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External IDSource
AN10956AspGD
orf19.5416CGD
4115DIP
2.3.1.48ExPASy
Z75152GenBank/EMBL/DDBJ
398365911GenBank/EMBL/DDBJ
CAA99465.1GenBank/EMBL/DDBJ
356624624GenBank/EMBL/DDBJ
356624622GenBank/EMBL/DDBJ
11513348GenBank/EMBL/DDBJ
Showing 1 to 10 of 45 entries

Resources