Phenotype Help

BRE5 / YNR051C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Non-essential gene; null mutant is heat sensitive, displays decreased competitive fitness on numerous growth media, has a decreased ability to utilize glucose as carbon source, and allantoin or glutamine as nitrogen sources; null mutant has abnormal nuclear morphology, filamentous and invasive growth defects, decreased stress resistance and a decreased ability to undergo ribophagy in response to nitrogen starvation; null mutant displays decreased resistance to cell wall stressors, antifungal agents and DNA synthesis inhibitors; null mutant has numerous alterations in the amino acid metabolome; null mutant has an increased replicative lifespan; null mutant has a defect in retrograde transport from the Golgi to the ER; homozygous diploid null displays a defect in meiosis with reduced gene conversion, and abnormal sporulation with an altered DL:LL dityrosine ratio; heterozygous diploid null mutant is haploproficient


A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

Gene Phenotype Experiment Type Mutant Information Strain Background Chemical Details Reference

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.