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TSA1 / YML028W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
cTPxI 13 , ZRG14 14 , TPX1
Protein Product
thioredoxin peroxidase TSA1
Feature Type
ORF , Verified
Description
Thioredoxin peroxidase; acts as both ribosome-associated and free cytoplasmic antioxidant; self-associates to form high-molecular weight chaperone complex under oxidative stress; chaperone activity essential for growth in zinc deficiency; required for telomere length maintenance; binds and modulates Cdc19p activity; protein abundance increases, forms cytoplasmic foci during DNA replication stress; TSA1 has a paralog, TSA2, that arose from the whole genome duplication 1 2 3 4 5 6 7 8 9 10 11 12
Paralog
TSA2 11
EC Number
1.11.1.15

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