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FPR4 / YLR449W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Protein Product
peptidylprolyl isomerase FPR4
Feature Type
ORF , Verified
Description
Peptidyl-prolyl cis-trans isomerase (PPIase); nuclear proline isomerase; affects expression of multiple genes via its role in nucleosome assembly; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; contains a nucleoplasmin-like fold and can form pentamers 1 2 3 4
Paralog
FPR3
EC Number
5.2.1.8

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