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SRS2 / YJL092W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
HPR5 15 , RADH 15 , RADH1
Protein Product
DNA helicase SRS2
Feature Type
ORF , Verified
Description
DNA helicase and DNA-dependent ATPase; role in DNA repair and checkpoint recovery, in the proper timing of commitment to meiotic recombination and the Meiosis I to II transition; blocks trinucleotide repeat expansion; affects genome stability; disassembles Rad51p nucleoprotein filaments during meiotic recombination; stimulates Mus81p-Mms4p endonuclease activity independent of catalytic activity; ATPase and ssDNA translocating motor activities inhibited by Dmc1p; functional homolog of human RTEL1 2 3 4 5 6 7 8 9 10 11 12 13 14
EC Number
3.6.4.12

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