Sequence Help

ERG26 / YGL001C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

Protein Product
sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating)
Feature Type
ORF , Verified
C-3 sterol dehydrogenase; catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; human homolog NSDHL implicated in CK syndrome, and can complement yeast null mutant; molecular target of natural product and antifungal compound FR171456 1 2 3 4 5 6
EC Number