Sequence Help

DOT1 / YDR440W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

KMT4 7 , PCH1 3
Protein Product
histone methyltransferase DOT1
Feature Type
ORF , Verified
Nucleosomal histone H3-Lys79 methylase; methylation is required for telomeric silencing, meiotic checkpoint control, and DNA damage response; single DOT1 gene produces two Dot1p isoforms from alternative translation start sites as a result of leaky scanning by the ribosome 2 3 4 5 6
EC Number