Sequence Help
NPL3 / YDR432W Sequence
Sequences and genome annotation information for Reference Strain S288C and a select set of
Alternative References.
- Aliases
-
NAB1
11
,
MTR13
12
,
MTS1
13
,
NOP3
14
- Protein Product
-
mRNA-binding protein NPL3
- Feature Type
- ORF
, Verified
- Description
-
RNA-binding protein; promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; represses translation initiation by binding eIF4G; required for pre-mRNA splicing; interacts with E3 ubiquitin ligase Bre1p, linking histone ubiquitination to mRNA processing; may have role in telomere maintenance; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in cytoplasm; protein abundance increases in response to DNA replication stress
2
3
4
5
6
7
8
9
10