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UME6 / YDR207C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
CAR80 1 2 , NIM2 , RIM16 25
Protein Product
DNA-binding transcriptional regulator UME6
Feature Type
ORF , Verified
Description
Rpd3L histone deacetylase complex subunit; key transcriptional regulator of early meiotic genes; involved in chromatin remodeling and transcriptional repression via DNA looping; binds URS1 upstream regulatory sequence, represses transcription by recruiting conserved histone deacetylase Rpd3p (through co-repressor Sin3p) and chromatin-remodeling factor Isw2p; couples metabolic responses to nutritional cues with initiation and progression of meiosis 2 3 4 5 6 7 8 9 11 12 13

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