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YPK1 / YKL126W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

Protein Product
serine/threonine protein kinase YPK1
Feature Type
ORF , Verified
S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant and the inviability of a ypk1 ypk2 double mutant 2 3 4 5 6 7 8 9 10 11
YPK2 9
EC Number