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SLD2 / YKL108W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
DRC1 4
Feature Type
ORF , Verified
Description
Single-stranded DNA origin-binding and annealing protein; required for initiation of DNA replication; phosphorylated in S phase by cyclin-dependent kinases (Cdks), promoting origin binding, DNA replication and Dpb11p complex formation; component of the preloading complex; binds the Mcm2-7p complex to prevent inappropriate Mcm2-7p interaction with the GINS complex in G1; required for S phase checkpoint; relative distribution to the nucleus increases upon DNA replication stress 2 3 4 5 6 7 8 9 10 11

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