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MEC1 / YBR136W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
ESR1 2 , SAD3 31 , RAD31 32
Protein Product
protein kinase MEC1
Feature Type
ORF , Verified
Description
Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres 1 2 3 4 5 6 7 8 9 10 11 12
EC Number
2.7.11.1

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