TEC1 / YBR083W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

TEC1/YBR083W is a non-essential gene in reference strain S288C; null mutants are viable and show decreased competitive fitness, decreased chronological lifespan, reduced utilization of glucose, ammonium, and allantoin, abnormal subcellular morphology, decreased transposable element transposition, and decreased resistance to rapamycin. In Sigma1278b, the null abolishes invasive growth, decreases filamentous growth and biofilm formation, delays budding, and causes abnormal colony appearance. Overexpression in S288C causes abnormal nuclear morphology, abnormal cell cycle progression, and reduced competitive fitness; in Sigma1278b it increases invasive and filamentous growth.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources