Gene Ontology Help

Phosphatidylinositol 3-kinase complex II Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Catalyzes phosphorylation of phosphatidyl inositol, one of the major phospholipids in the cell, specifically at the d-3 position of the inositol ring, to generate PtdIns(3)P. Directs the synthesis of a specific endosomal pool of PtdIns3P, which is required for recruitment/activation of the retromer complex, thereby ensuring efficient endosome-to-Golgi retrograde transport.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

ion binding, kinase activity, transferase activity, biosynthetic process, lipid metabolic process, transport, vacuolar transport, vesicle-mediated transport, membrane