Primary Literature
TEXT HERE
- Hancock LP, et al. (2025) Agent-based modelling of the early stages of actin polymerisation required to drive endocytosis in Saccharomyces cerevisiae. Sci Rep 15(1):28951 PMID: 40775504
- Zhou FY, et al. (2025) Arp2/3 and type-I myosins control chromosome mobility and end-resection at double-strand breaks in S. cerevisiae. Nat Commun 16(1):7212 PMID: 40764615
- Narvaez-Ortiz HY, et al. (2024) Both Las17-binding sites on Arp2/3 complex are important for branching nucleation and assembly of functional endocytic actin networks in S. cerevisiae. J Biol Chem 300(3):105766 PMID: 38367669
- Liu D, et al. (2022) ER-phagy requires the assembly of actin at sites of contact between the cortical ER and endocytic pits. Proc Natl Acad Sci U S A 119(6) PMID: 35101986
- Muller R, et al. (2020) CiBER-seq dissects genetic networks by quantitative CRISPRi profiling of expression phenotypes. Science 370(6522) PMID: 33303588
- Pedersen RTA and Drubin DG (2019) Type I myosins anchor actin assembly to the plasma membrane during clathrin-mediated endocytosis. J Cell Biol 218(4):1138-1147 PMID: 30659101
- Sun G, et al. (2019) The tomato Arp2/3 complex is required for resistance to the powdery mildew fungus Oidium neolycopersici. Plant Cell Environ 42(9):2664-2680 PMID: 31038756
- Sun Y, et al. (2019) Direct comparison of clathrin-mediated endocytosis in budding and fission yeast reveals conserved and evolvable features. Elife 8 PMID: 31829937
- Goode BL, et al. (2018) GMF as an Actin Network Remodeling Factor. Trends Cell Biol 28(9):749-760 PMID: 29779865
- Guo S, et al. (2018) Abp1 promotes Arp2/3 complex-dependent actin nucleation and stabilizes branch junctions by antagonizing GMF. Nat Commun 9(1):2895 PMID: 30042427
- Hinze C and Boucrot E (2018) Local actin polymerization during endocytic carrier formation. Biochem Soc Trans 46(3):565-576 PMID: 29678956
- Luan Q, et al. (2018) Identification of Wiskott-Aldrich syndrome protein (WASP) binding sites on the branched actin filament nucleator Arp2/3 complex. Proc Natl Acad Sci U S A 115(7):E1409-E1418 PMID: 29386393
- Yamagishi Y, et al. (2018) Use of CK-548 and CK-869 as Arp2/3 complex inhibitors directly suppresses microtubule assembly both in vitro and in vivo. Biochem Biophys Res Commun 496(3):834-839 PMID: 29395083
- Farrell KB, et al. (2017) Novel function of a dynein light chain in actin assembly during clathrin-mediated endocytosis. J Cell Biol 216(8):2565-2580 PMID: 28706108
- Sokolova OS, et al. (2017) Structural Basis of Arp2/3 Complex Inhibition by GMF, Coronin, and Arpin. J Mol Biol 429(2):237-248 PMID: 27939292
- Yabuki Y, et al. (2017) Arp2/3 complex and Mps3 are required for regulation of ribosome biosynthesis in the secretory stress response. Yeast 34(4):155-163 PMID: 27862269
- Rodnick-Smith M, et al. (2016) Role and structural mechanism of WASP-triggered conformational changes in branched actin filament nucleation by Arp2/3 complex. Proc Natl Acad Sci U S A 113(27):E3834-43 PMID: 27325766
- Rodnick-Smith M, et al. (2016) Identification of an ATP-controlled allosteric switch that controls actin filament nucleation by Arp2/3 complex. Nat Commun 7:12226 PMID: 27417392
- Wang X, et al. (2016) Actin-Regulator Feedback Interactions during Endocytosis. Biophys J 110(6):1430-43 PMID: 27028652
- Feliciano D, et al. (2015) A second Las17 monomeric actin-binding motif functions in Arp2/3-dependent actin polymerization during endocytosis. Traffic 16(4):379-97 PMID: 25615019
- Encinar del Dedo J, et al. (2014) Eng2 is a component of a dynamic protein complex required for endocytic uptake in fission yeast. Traffic 15(10):1122-42 PMID: 25040903
- Yen EA, et al. (2014) Exploration of the dynamic properties of protein complexes predicted from spatially constrained protein-protein interaction networks. PLoS Comput Biol 10(5):e1003654 PMID: 24874694
- Doolittle LK, et al. (2013) Purification of Arp2/3 complex from Saccharomyces cerevisiae. Methods Mol Biol 1046:251-71 PMID: 23868593
- Ingerman E, et al. (2013) Arp2/3 complex ATP hydrolysis promotes lamellipodial actin network disassembly but is dispensable for assembly. J Cell Biol 200(5):619-33 PMID: 23439681
- Liu SL, et al. (2013) Insertions within the actin core of actin-related protein 3 (Arp3) modulate branching nucleation by Arp2/3 complex. J Biol Chem 288(1):487-97 PMID: 23148219
- Schubert HL, et al. (2013) Structure of an actin-related subcomplex of the SWI/SNF chromatin remodeler. Proc Natl Acad Sci U S A 110(9):3345-50 PMID: 23401505
- Smith BA, et al. (2013) Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation. Elife 2:e01008 PMID: 24015360
- Smith BA, et al. (2013) Pathway of actin filament branch formation by Arp2/3 complex revealed by single-molecule imaging. Proc Natl Acad Sci U S A 110(4):1285-90 PMID: 23292935
- Ydenberg CA, et al. (2013) GMF severs actin-Arp2/3 complex branch junctions by a cofilin-like mechanism. Curr Biol 23(12):1037-45 PMID: 23727094
- Feliciano D and Di Pietro SM (2012) SLAC, a complex between Sla1 and Las17, regulates actin polymerization during clathrin-mediated endocytosis. Mol Biol Cell 23(21):4256-72 PMID: 22973053
- Galletta BJ, et al. (2012) Molecular analysis of Arp2/3 complex activation in cells. Biophys J 103(10):2145-56 PMID: 23200048
- Idrissi FZ, et al. (2012) Ultrastructural dynamics of proteins involved in endocytic budding. Proc Natl Acad Sci U S A 109(39):E2587-94 PMID: 22949647
- Kruth KA and Rubenstein PA (2012) Two deafness-causing (DFNA20/26) actin mutations affect Arp2/3-dependent actin regulation. J Biol Chem 287(32):27217-26 PMID: 22718764
- Cabrera R, et al. (2011) Schizosaccharomyces pombe Arc3 is a conserved subunit of the Arp2/3 complex required for polarity, actin organization, and endocytosis. Yeast 28(6):495-503 PMID: 21449051
- Giblin J, et al. (2011) Function and regulation of Saccharomyces cerevisiae myosins-I in endocytic budding. Biochem Soc Trans 39(5):1185-90 PMID: 21936786
- Liu SL, et al. (2011) Mechanism of a concentration-dependent switch between activation and inhibition of Arp2/3 complex by coronin. J Biol Chem 286(19):17039-46 PMID: 21454476
- Prosser DC, et al. (2011) Existence of a novel clathrin-independent endocytic pathway in yeast that depends on Rho1 and formin. J Cell Biol 195(4):657-71 PMID: 22065638
- Balcer HI, et al. (2010) The p40/ARPC1 subunit of Arp2/3 complex performs multiple essential roles in WASp-regulated actin nucleation. J Biol Chem 285(11):8481-91 PMID: 20071330
- Epp E, et al. (2010) Forward genetics in Candida albicans that reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis. Mol Microbiol 75(5):1182-98 PMID: 20141603
- Gandhi M, et al. (2010) GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation. Curr Biol 20(9):861-7 PMID: 20362448
- Gandhi M, et al. (2010) Functional surfaces on the actin-binding protein coronin revealed by systematic mutagenesis. J Biol Chem 285(45):34899-908 PMID: 20813846
- Grötsch H, et al. (2010) Calmodulin dissociation regulates Myo5 recruitment and function at endocytic sites. EMBO J 29(17):2899-914 PMID: 20647997
- Yamamoto T, et al. (2010) Initial polarized bud growth by endocytic recycling in the absence of actin cable-dependent vesicle transport in yeast. Mol Biol Cell 21(7):1237-52 PMID: 20147449
- Boettner DR, et al. (2009) The F-BAR protein Syp1 negatively regulates WASp-Arp2/3 complex activity during endocytic patch formation. Curr Biol 19(23):1979-87 PMID: 19962315
- Rajmohan R, et al. (2009) Las17p-Vrp1p but not Las17p-Arp2/3 interaction is important for actin patch polarization in yeast. Biochim Biophys Acta 1793(5):825-35 PMID: 19272406
- Rizvi SA, et al. (2009) Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly. Chem Biol 16(11):1158-68 PMID: 19942139
- Shvetsov A, et al. (2009) The actin-binding domain of cortactin is dynamic and unstructured and affects lateral and longitudinal contacts in F-actin. Cell Motil Cytoskeleton 66(2):90-8 PMID: 19089942
- Daugherty KM and Goode BL (2008) Functional surfaces on the p35/ARPC2 subunit of Arp2/3 complex required for cell growth, actin nucleation, and endocytosis. J Biol Chem 283(24):16950-9 PMID: 18381280
- Galletta BJ, et al. (2008) Distinct roles for Arp2/3 regulators in actin assembly and endocytosis. PLoS Biol 6(1):e1 PMID: 18177206
- Monastyrska I, et al. (2008) Arp2 links autophagic machinery with the actin cytoskeleton. Mol Biol Cell 19(5):1962-75 PMID: 18287533
- Monastyrska I, et al. (2008) Harpooning the Cvt complex to the phagophore assembly site. Autophagy 4(7):914-6 PMID: 18708760
- Rouiller I, et al. (2008) The structural basis of actin filament branching by the Arp2/3 complex. J Cell Biol 180(5):887-95 PMID: 18316411
- Valiathan RR and Weisman LS (2008) Pushing for answers: is myosin V directly involved in moving mitochondria? J Cell Biol 181(1):15-8 PMID: 18391069
- Deeks MJ, et al. (2007) Arabidopsis CAP1 - a key regulator of actin organisation and development. J Cell Sci 120(Pt 15):2609-18 PMID: 17635992
- GarcÃa-RodrÃguez LJ, et al. (2007) Puf3p, a Pumilio family RNA binding protein, localizes to mitochondria and regulates mitochondrial biogenesis and motility in budding yeast. J Cell Biol 176(2):197-207 PMID: 17210948
- Toshima J, et al. (2007) Negative regulation of yeast Eps15-like Arp2/3 complex activator, Pan1p, by the Hip1R-related protein, Sla2p, during endocytosis. Mol Biol Cell 18(2):658-68 PMID: 17151356
- Goley ED and Welch MD (2006) The ARP2/3 complex: an actin nucleator comes of age. Nat Rev Mol Cell Biol 7(10):713-26 PMID: 16990851
- Kim K, et al. (2006) Actin-based motility during endocytosis in budding yeast. Mol Biol Cell 17(3):1354-63 PMID: 16394096
- Kovar DR (2006) Arp2/3 ATP hydrolysis: to branch or to debranch? Nat Cell Biol 8(8):783-5 PMID: 16880808
- Martin AC, et al. (2006) Arp2/3 ATP hydrolysis-catalysed branch dissociation is critical for endocytic force generation. Nat Cell Biol 8(8):826-33 PMID: 16862144
- Chang FS, et al. (2005) A WASp-binding type II phosphatidylinositol 4-kinase required for actin polymerization-driven endosome motility. J Cell Biol 171(1):133-42 PMID: 16216926
- D'Agostino JL and Goode BL (2005) Dissection of Arp2/3 complex actin nucleation mechanism and distinct roles for its nucleation-promoting factors in Saccharomyces cerevisiae. Genetics 171(1):35-47 PMID: 16183906
- Fehrenbacher KL, et al. (2005) A role for Jsn1p in recruiting the Arp2/3 complex to mitochondria in budding yeast. Mol Biol Cell 16(11):5094-102 PMID: 16107558
- Kamińska J, et al. (2005) Pan1p, an actin cytoskeleton-associated protein, is required for growth of yeast on oleate medium. Exp Cell Res 310(2):482-92 PMID: 16171804
- Martin AC, et al. (2005) Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function. J Cell Biol 168(2):315-28 PMID: 15657399
- McKane M, et al. (2005) A mammalian actin substitution in yeast actin (H372R) causes a suppressible mitochondria/vacuole phenotype. J Biol Chem 280(43):36494-501 PMID: 16118223
- Quintero-Monzon O, et al. (2005) Structural and functional dissection of the Abp1 ADFH actin-binding domain reveals versatile in vivo adapter functions. Mol Biol Cell 16(7):3128-39 PMID: 15872087
- Rodal AA, et al. (2005) Actin and septin ultrastructures at the budding yeast cell cortex. Mol Biol Cell 16(1):372-84 PMID: 15525671
- Rodal AA, et al. (2005) Conformational changes in the Arp2/3 complex leading to actin nucleation. Nat Struct Mol Biol 12(1):26-31 PMID: 15592479
- Sirotkin V, et al. (2005) Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex during actin patch assembly in fission yeast. J Cell Biol 170(4):637-48 PMID: 16087707
- Toshima J, et al. (2005) Phosphoregulation of Arp2/3-dependent actin assembly during receptor-mediated endocytosis. Nat Cell Biol 7(3):246-54 PMID: 15711538
- Wen KK and Rubenstein PA (2005) Acceleration of yeast actin polymerization by yeast Arp2/3 complex does not require an Arp2/3-activating protein. J Biol Chem 280(25):24168-74 PMID: 15857833
- Beltzner CC and Pollard TD (2004) Identification of functionally important residues of Arp2/3 complex by analysis of homology models from diverse species. J Mol Biol 336(2):551-65 PMID: 14757065
- Boldogh IR, et al. (2004) A type V myosin (Myo2p) and a Rab-like G-protein (Ypt11p) are required for retention of newly inherited mitochondria in yeast cells during cell division. Mol Biol Cell 15(9):3994-4002 PMID: 15215313
- Fehrenbacher KL, et al. (2004) Live cell imaging of mitochondrial movement along actin cables in budding yeast. Curr Biol 14(22):1996-2004 PMID: 15556861
- Huckaba TM, et al. (2004) Live cell imaging of the assembly, disassembly, and actin cable-dependent movement of endosomes and actin patches in the budding yeast, Saccharomyces cerevisiae. J Cell Biol 167(3):519-30 PMID: 15534003
- Jonsdottir GA and Li R (2004) Dynamics of yeast Myosin I: evidence for a possible role in scission of endocytic vesicles. Curr Biol 14(17):1604-9 PMID: 15341750
- Kawai S, et al. (2004) Molecular insights on DNA delivery into Saccharomyces cerevisiae. Biochem Biophys Res Commun 317(1):100-7 PMID: 15047153
- Kovar DR and Pollard TD (2004) Insertional assembly of actin filament barbed ends in association with formins produces piconewton forces. Proc Natl Acad Sci U S A 101(41):14725-30 PMID: 15377785
- Millard TH, et al. (2004) Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex. Biochem J 380(Pt 1):1-17 PMID: 15040784
- Norden C, et al. (2004) Dissection of septin actin interactions using actin overexpression in Saccharomyces cerevisiae. Mol Microbiol 53(2):469-83 PMID: 15228528
- Pan F, et al. (2004) ARPC1/Arc40 mediates the interaction of the actin-related protein 2 and 3 complex with Wiskott-Aldrich syndrome protein family activators. J Biol Chem 279(52):54629-36 PMID: 15485833
- Young ME, et al. (2004) Yeast actin patches are networks of branched actin filaments. J Cell Biol 166(5):629-35 PMID: 15337772
- Chang FS, et al. (2003) A WASp homolog powers actin polymerization-dependent motility of endosomes in vivo. Curr Biol 13(6):455-63 PMID: 12646127
- Evangelista M, et al. (2003) Formins: signaling effectors for assembly and polarization of actin filaments. J Cell Sci 116(Pt 13):2603-11 PMID: 12775772
- Fehrenbacher K, et al. (2003) Actin comet tails, endosomes and endosymbionts. J Exp Biol 206(Pt 12):1977-84 PMID: 12756279
- Friesen H, et al. (2003) Regulation of the yeast amphiphysin homologue Rvs167p by phosphorylation. Mol Biol Cell 14(7):3027-40 PMID: 12857883
- Kreishman-Deitrick M, et al. (2003) NMR analysis of methyl groups at 100-500 kDa: model systems and Arp2/3 complex. Biochemistry 42(28):8579-86 PMID: 12859205
- Rodal AA, et al. (2003) Negative regulation of yeast WASp by two SH3 domain-containing proteins. Curr Biol 13(12):1000-8 PMID: 12814545
- Schaerer-Brodbeck C and Riezman H (2003) Genetic and biochemical interactions between the Arp2/3 complex, Cmd1p, casein kinase II, and Tub4p in yeast. FEMS Yeast Res 4(1):37-49 PMID: 14554195
- Weaver AM, et al. (2003) Integration of signals to the Arp2/3 complex. Curr Opin Cell Biol 15(1):23-30 PMID: 12517700
- Eitzen G, et al. (2002) Remodeling of organelle-bound actin is required for yeast vacuole fusion. J Cell Biol 158(4):669-79 PMID: 12177043
- Evangelista M, et al. (2002) Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast. Nat Cell Biol 4(1):32-41 PMID: 11740490
- Evangelista M, et al. (2002) Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast. Nat Cell Biol 4(3):260-9 PMID: 11875440
- Humphries CL, et al. (2002) Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin. J Cell Biol 159(6):993-1004 PMID: 12499356
- Idrissi FZ, et al. (2002) Cofilin, but not profilin, is required for myosin-I-induced actin polymerization and the endocytic uptake in yeast. Mol Biol Cell 13(11):4074-87 PMID: 12429847
- Pruyne D, et al. (2002) Role of formins in actin assembly: nucleation and barbed-end association. Science 297(5581):612-5 PMID: 12052901
- Qualmann B and Kessels MM (2002) Endocytosis and the cytoskeleton. Int Rev Cytol 220:93-144 PMID: 12224553
- Sagot I, et al. (2002) An actin nucleation mechanism mediated by Bni1 and profilin. Nat Cell Biol 4(8):626-31 PMID: 12134165
- Schafer DA (2002) Coupling actin dynamics and membrane dynamics during endocytosis. Curr Opin Cell Biol 14(1):76-81 PMID: 11792548
- Soulard A, et al. (2002) Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro. Mol Cell Biol 22(22):7889-906 PMID: 12391157
- Tolliday N, et al. (2002) Rho1 directs formin-mediated actin ring assembly during budding yeast cytokinesis. Curr Biol 12(21):1864-70 PMID: 12419188
- Warren DT, et al. (2002) Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics. J Cell Sci 115(Pt 8):1703-15 PMID: 11950888
- Zettl M and Way M (2002) The WH1 and EVH1 domains of WASP and Ena/VASP family members bind distinct sequence motifs. Curr Biol 12(18):1617-22 PMID: 12372256
- Boldogh IR, et al. (2001) Arp2/3 complex and actin dynamics are required for actin-based mitochondrial motility in yeast. Proc Natl Acad Sci U S A 98(6):3162-7 PMID: 11248049
- Duncan MC, et al. (2001) Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex. Nat Cell Biol 3(7):687-90 PMID: 11433303
- Goode BL, et al. (2001) Activation of the Arp2/3 complex by the actin filament binding protein Abp1p. J Cell Biol 153(3):627-34 PMID: 11331312
- Olazabal IM and Machesky LM (2001) Abp1p and cortactin, new "hand-holds" for actin. J Cell Biol 154(4):679-82 PMID: 11514584
- Robinson RC, et al. (2001) Crystal structure of Arp2/3 complex. Science 294(5547):1679-84 PMID: 11721045
- Volkmann N, et al. (2001) Structure of Arp2/3 complex in its activated state and in actin filament branch junctions. Science 293(5539):2456-9 PMID: 11533442
- Evangelista M, et al. (2000) A role for myosin-I in actin assembly through interactions with Vrp1p, Bee1p, and the Arp2/3 complex. J Cell Biol 148(2):353-62 PMID: 10648568
- Lechler T, et al. (2000) Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization. J Cell Biol 148(2):363-73 PMID: 10648569
- Lee WL, et al. (2000) Fission yeast myosin-I, Myo1p, stimulates actin assembly by Arp2/3 complex and shares functions with WASp. J Cell Biol 151(4):789-800 PMID: 11076964
- Schaerer-Brodbeck C and Riezman H (2000) Saccharomyces cerevisiae Arc35p works through two genetically separable calmodulin functions to regulate the actin and tubulin cytoskeletons. J Cell Sci 113 ( Pt 3):521-32 PMID: 10639338
- Schaerer-Brodbeck C and Riezman H (2000) Functional interactions between the p35 subunit of the Arp2/3 complex and calmodulin in yeast. Mol Biol Cell 11(4):1113-27 PMID: 10749918
- Feoktistova A, et al. (1999) Identification and characterization of Schizosaccharomyces pombe asp1(+), a gene that interacts with mutations in the Arp2/3 complex and actin. Genetics 152(3):895-908 PMID: 10388810
- Higgs HN, et al. (1999) Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization. Biochemistry 38(46):15212-22 PMID: 10563804
- Machesky LM and Gould KL (1999) The Arp2/3 complex: a multifunctional actin organizer. Curr Opin Cell Biol 11(1):117-21 PMID: 10047519
- Madania A, et al. (1999) The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex. Mol Biol Cell 10(10):3521-38 PMID: 10512884
- Morrell JL, et al. (1999) A mutant of Arp2p causes partial disassembly of the Arp2/3 complex and loss of cortical actin function in fission yeast. Mol Biol Cell 10(12):4201-15 PMID: 10588653
- Mullins RD and Pollard TD (1999) Structure and function of the Arp2/3 complex. Curr Opin Struct Biol 9(2):244-9 PMID: 10322212
- Winter DC, et al. (1999) Genetic dissection of the budding yeast Arp2/3 complex: a comparison of the in vivo and structural roles of individual subunits. Proc Natl Acad Sci U S A 96(13):7288-93 PMID: 10377407
- Winter D, et al. (1999) Activation of the yeast Arp2/3 complex by Bee1p, a WASP-family protein. Curr Biol 9(9):501-4 PMID: 10322115
- Mullins RD, et al. (1997) Structure, subunit topology, and actin-binding activity of the Arp2/3 complex from Acanthamoeba. J Cell Biol 136(2):331-43 PMID: 9015304
- Welch MD, et al. (1997) The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. J Cell Biol 138(2):375-84 PMID: 9230079
- Welch MD, et al. (1997) Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes. Nature 385(6613):265-9 PMID: 9000076
- Winter D, et al. (1997) The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches. Curr Biol 7(7):519-29 PMID: 9210376