Reference: Mikhaĭlova NP, et al. (1990) [Sterol level in Saccharomyces cerevisiae mutants with altered ergosterol biosynthesis]. Prikl Biokhim Mikrobiol 26(3):360-3

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Abstract


The sterol content in Saccharomyces cerevisiae mutants defective in the synthesis of cyclic ergosterol precursors has been studied. It was found that strains with mutational blocks involving the stages of zymosterol side chain methylation at C24 and delta 8----delta 7 isomerization accumulated twice more sterols as compared to parent strains. Regulation of the ergosterol biosynthesis is discussed.

Reference Type
Journal Article
Authors
Mikhaĭlova NP, Ogorodnikova TE, V'iunov KA
Additional Lit For
ERG2