Reference: Bishop DK and Zickler D (2004) Early decision; meiotic crossover interference prior to stable strand exchange and synapsis. Cell 117(1):9-15

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Abstract


During meiosis, DNA double-strand breaks ultimately yield two types of recombinants: crossovers (CO) and noncrossovers (NCO). Recent studies in budding yeast show the CO/NCO designation occurs before stable strand exchange and thus well before Holliday junction resolution. Chromosome synapsis occurs after CO/NCO designation and is not required for the regulated distribution of COs along chromosomes manifested as CO interference.

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Comment | Journal Article | Review
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Bishop DK, Zickler D
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