Literature Help
HED1 / YDR014W-A Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Woo TT, et al. (2020) Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks. Nucleic Acids Res 48(15):8474-8489 PMID:32652040
- Crickard JB, et al. (2018) Meiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinase. Proc Natl Acad Sci U S A 115(43):E10041-E10048 PMID:30301803
- Kong YJ, et al. (2017) Hed1 Promotes Meiotic Crossover Formation in Saccharomyces cerevisiae. J Microbiol Biotechnol 27(2):405-411 PMID:27974736
- Callender TL, et al. (2016) Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1. PLoS Genet 12(8):e1006226 PMID:27483004
- Hong S, et al. (2013) The logic and mechanism of homologous recombination partner choice. Mol Cell 51(4):440-53 PMID:23973374
- Lao JP, et al. (2013) Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation. PLoS Genet 9(12):e1003978 PMID:24367271
- Busygina V, et al. (2012) Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiotic recombination. J Biol Chem 287(2):1566-75 PMID:22115747
- Busygina V, et al. (2008) Hed1 regulates Rad51-mediated recombination via a novel mechanism. Genes Dev 22(6):786-95 PMID:18347097
- Tsubouchi H and Roeder GS (2006) Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired. Genes Dev 20(13):1766-75 PMID:16818607
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
Reset
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Park ZM, et al. (2023) Kar4 is required for the normal pattern of meiotic gene expression. PLoS Genet 19(8):e1010898 PMID:37639444
- Scutenaire J, et al. (2023) The S. cerevisiae m6A-reader Pho92 promotes timely meiotic recombination by controlling key methylated transcripts. Nucleic Acids Res 51(2):517-535 PMID:35934316
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Cloud V, et al. (2012) Rad51 is an accessory factor for Dmc1-mediated joint molecule formation during meiosis. Science 337(6099):1222-5 PMID:22955832
- Niu H, et al. (2009) Regulation of meiotic recombination via Mek1-mediated Rad54 phosphorylation. Mol Cell 36(3):393-404 PMID:19917248
Reviews
No reviews curated.
Download References (.nbib)
- Woo TT, et al. (2021) Budding yeast Rad51: a paradigm for how phosphorylation and intrinsic structural disorder regulate homologous recombination and protein homeostasis. Curr Genet 67(3):389-396 PMID:33433732
- Jensen MK (2018) Design principles for nuclease-deficient CRISPR-based transcriptional regulators. FEMS Yeast Res 18(4) PMID:29726937
- Lian J, et al. (2018) Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System. Biotechnol J 13(9):e1700601 PMID:29436783
- Humphryes N and Hochwagen A (2014) A non-sister act: recombination template choice during meiosis. Exp Cell Res 329(1):53-60 PMID:25158281
- Pradillo M, et al. (2014) On the role of AtDMC1, AtRAD51 and its paralogs during Arabidopsis meiosis. Front Plant Sci 5:23 PMID:24596572
- Krejci L, et al. (2012) Homologous recombination and its regulation. Nucleic Acids Res 40(13):5795-818 PMID:22467216
- Pradillo M and Santos JL (2011) The template choice decision in meiosis: is the sister important? Chromosoma 120(5):447-54 PMID:21826413
- Hollingsworth NM (2010) Phosphorylation and the creation of interhomolog bias during meiosis in yeast. Cell Cycle 9(3):436-7 PMID:20090416
- Holloman WK, et al. (2008) The homologous recombination system of Ustilago maydis. Fungal Genet Biol 45 Suppl 1(Suppl 1):S31-9 PMID:18502156
- Sheridan S and Bishop DK (2006) Red-Hed regulation: recombinase Rad51, though capable of playing the leading role, may be relegated to supporting Dmc1 in budding yeast meiosis. Genes Dev 20(13):1685-91 PMID:16818601
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Callender TL, et al. (2016) Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1. PLoS Genet 12(8):e1006226 PMID:27483004
- Lao JP, et al. (2013) Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation. PLoS Genet 9(12):e1003978 PMID:24367271
- Busygina V, et al. (2008) Hed1 regulates Rad51-mediated recombination via a novel mechanism. Genes Dev 22(6):786-95 PMID:18347097
- Tsubouchi H and Roeder GS (2006) Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired. Genes Dev 20(13):1766-75 PMID:16818607
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Weng Q, et al. (2024) An acidic loop in the forkhead-associated domain of the yeast meiosis-specific kinase Mek1 interacts with a specific motif in a subset of Mek1 substrates. Genetics 228(1) PMID:38979911
- Morciano L, et al. (2023) Homologous Recombination and Repair Functions Required for Mutagenicity during Yeast Meiosis. Genes (Basel) 14(11) PMID:38002960
- Scutenaire J, et al. (2023) The S. cerevisiae m6A-reader Pho92 promotes timely meiotic recombination by controlling key methylated transcripts. Nucleic Acids Res 51(2):517-535 PMID:35934316
- Ziesel A, et al. (2022) Rad51-mediated interhomolog recombination during budding yeast meiosis is promoted by the meiotic recombination checkpoint and the conserved Pif1 helicase. PLoS Genet 18(12):e1010407 PMID:36508468
- Woo TT, et al. (2020) Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks. Nucleic Acids Res 48(15):8474-8489 PMID:32652040
- Crickard JB, et al. (2018) Regulation of Hed1 and Rad54 binding during maturation of the meiosis-specific presynaptic complex. EMBO J 37(7) PMID:29444896
- Callender TL, et al. (2016) Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1. PLoS Genet 12(8):e1006226 PMID:27483004
- Penedos A, et al. (2015) Essential and Checkpoint Functions of Budding Yeast ATM and ATR during Meiotic Prophase Are Facilitated by Differential Phosphorylation of a Meiotic Adaptor Protein, Hop1. PLoS One 10(7):e0134297 PMID:26225562
- Liu Y, et al. (2014) Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair of double-strand breaks. PLoS Genet 10(1):e1004005 PMID:24465215
- Lao JP, et al. (2013) Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation. PLoS Genet 9(12):e1003978 PMID:24367271
- Busygina V, et al. (2012) Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiotic recombination. J Biol Chem 287(2):1566-75 PMID:22115747
- Busygina V, et al. (2008) Hed1 regulates Rad51-mediated recombination via a novel mechanism. Genes Dev 22(6):786-95 PMID:18347097
- Tsubouchi H and Roeder GS (2006) Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired. Genes Dev 20(13):1766-75 PMID:16818607
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Harris A and Ünal E (2023) The transcriptional regulator Ume6 is a major driver of early gene expression during gametogenesis. Genetics 225(2) PMID:37431893
- Callender TL, et al. (2016) Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1. PLoS Genet 12(8):e1006226 PMID:27483004
- Ostrow AZ, et al. (2014) Fkh1 and Fkh2 bind multiple chromosomal elements in the S. cerevisiae genome with distinct specificities and cell cycle dynamics. PLoS One 9(2):e87647 PMID:24504085