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SKI3 / YPR189W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

SKI5 21
Protein Product
SKI complex subunit tetratricopeptide repeat protein SKI3
Feature Type
ORF , Verified
Ski complex component and TPR protein; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, TTC37, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome 1 3 4 5 6