Literature Help
BET2 / YPR176C Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Tateishi M, et al. (2025) Double prenylation of budding yeast Ykt6 regulates cell wall integrity and autophagy. J Biol Chem 301(4):108384 PMID:40049413
- Chen HQ, et al. (2022) Identification of Kic1p and Cdc42p as Novel Targets to Engineer Yeast Acetic Acid Stress Tolerance. Front Bioeng Biotechnol 10:837813 PMID:35402407
- Wang Y, et al. (2018) The cellular economy of the Saccharomyces cerevisiae zinc proteome. Metallomics 10(12):1755-1776 PMID:30358795
- Eapen VV, et al. (2017) A pathway of targeted autophagy is induced by DNA damage in budding yeast. Proc Natl Acad Sci U S A 114(7):E1158-E1167 PMID:28154131
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Kachroo AH, et al. (2015) Evolution. Systematic humanization of yeast genes reveals conserved functions and genetic modularity. Science 348(6237):921-5 PMID:25999509
- Wang J, et al. (2015) Ypt1/Rab1 regulates Hrr25/CK1δ kinase activity in ER-Golgi traffic and macroautophagy. J Cell Biol 210(2):273-85 PMID:26195667
- Sukhai MA, et al. (2013) Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors. J Clin Invest 123(1):315-28 PMID:23202731
- Witter DJ and Poulter CD (1996) Yeast geranylgeranyltransferase type-II: steady state kinetic studies of the recombinant enzyme. Biochemistry 35(32):10454-63 PMID:8756702
- Jiang Y, et al. (1995) BTS1 encodes a geranylgeranyl diphosphate synthase in Saccharomyces cerevisiae. J Biol Chem 270(37):21793-9 PMID:7665600
- Jiang Y, et al. (1995) Characterization of yeast type-II geranylgeranyltransferase. Methods Enzymol 257:21-9 PMID:8583924
- Jiang Y and Ferro-Novick S (1994) Identification of yeast component A: reconstitution of the geranylgeranyltransferase that modifies Ypt1p and Sec4p. Proc Natl Acad Sci U S A 91(10):4377-81 PMID:8183917
- Jiang Y, et al. (1993) Bet2p and Mad2p are components of a prenyltransferase that adds geranylgeranyl onto Ypt1p and Sec4p. Nature 366(6450):84-6 PMID:8232542
- Li R, et al. (1993) The mitotic feedback control gene MAD2 encodes the alpha-subunit of a prenyltransferase. Nature 366(6450):82-4 PMID:8232541
- Rossi G, et al. (1991) Dependence of Ypt1 and Sec4 membrane attachment on Bet2. Nature 351(6322):158-61 PMID:1903184
- Newman AP, et al. (1990) BET1, BOS1, and SEC22 are members of a group of interacting yeast genes required for transport from the endoplasmic reticulum to the Golgi complex. Mol Cell Biol 10(7):3405-14 PMID:2192256
- Newman AP and Ferro-Novick S (1987) Characterization of new mutants in the early part of the yeast secretory pathway isolated by a [3H]mannose suicide selection. J Cell Biol 105(4):1587-94 PMID:3312234
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
Reset
Click on a gene or a paper to go to its specific page within SGD. Drag any of the gene or paper objects around
within the visualization for easier viewing and click “Reset” to automatically redraw the diagram.
Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Purchal MK, et al. (2022) Pseudouridine synthase 7 is an opportunistic enzyme that binds and modifies substrates with diverse sequences and structures. Proc Natl Acad Sci U S A 119(4) PMID:35058356
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Nawaz-ul-Rehman MS, et al. (2013) Yeast screens for host factors in positive-strand RNA virus replication based on a library of temperature-sensitive mutants. Methods 59(2):207-16 PMID:23147170
- Tang X, et al. (2013) Clustering based on multiple biological information: approach for predicting protein complexes. IET Syst Biol 7(5):223-30 PMID:24067423
- Chesi A, et al. (2012) The role of the Parkinson's disease gene PARK9 in essential cellular pathways and the manganese homeostasis network in yeast. PLoS One 7(3):e34178 PMID:22457822
- Li Z, et al. (2011) Systematic exploration of essential yeast gene function with temperature-sensitive mutants. Nat Biotechnol 29(4):361-7 PMID:21441928
- Garza RM, et al. (2009) Geranylgeranyl pyrophosphate is a potent regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA reductase degradation in yeast. J Biol Chem 284(51):35368-80 PMID:19776008
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Qi Y, et al. (2008) Finding friends and enemies in an enemies-only network: a graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions. Genome Res 18(12):1991-2004 PMID:18832443
- Szklarczyk R, et al. (2008) Complex fate of paralogs. BMC Evol Biol 8:337 PMID:19094234
- Wu D, et al. (2007) Covert genetic selections to optimize phenotypes. PLoS One 2(11):e1200 PMID:18030334
- Lai LC, et al. (2005) Dynamical remodeling of the transcriptome during short-term anaerobiosis in Saccharomyces cerevisiae: differential response and role of Msn2 and/or Msn4 and other factors in galactose and glucose media. Mol Cell Biol 25(10):4075-91 PMID:15870279
- Dimster-Denk D, et al. (1999) Comprehensive evaluation of isoprenoid biosynthesis regulation in Saccharomyces cerevisiae utilizing the Genome Reporter Matrix. J Lipid Res 40(5):850-60 PMID:10224154
- Fujimura K, et al. (1994) The Saccharomyces cerevisiae MSI4 gene encodes the yeast counterpart of component A of Rab geranylgeranyltransferase. J Biol Chem 269(12):9205-12 PMID:8132658
- Armstrong SA, et al. (1993) cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase. J Biol Chem 268(16):12221-9 PMID:8505342
- Díaz M, et al. (1993) The Schizosaccharomyces pombe cwg2+ gene codes for the beta subunit of a geranylgeranyltransferase type I required for beta-glucan synthesis. EMBO J 12(13):5245-54 PMID:8262067
- Kohl NE, et al. (1991) Structural homology among mammalian and Saccharomyces cerevisiae isoprenyl-protein transferases. J Biol Chem 266(28):18884-8 PMID:1918005
- Ohya Y, et al. (1991) Yeast CAL1 is a structural and functional homologue to the DPR1 (RAM) gene involved in ras processing. J Biol Chem 266(19):12356-60 PMID:2061313
- Petersen-Bjørn S, et al. (1990) An essential gene in Saccharomyces cerevisiae shares an upstream regulatory element with PRP4. Yeast 6(4):345-52 PMID:2204247
Reviews
No reviews curated.
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Tateishi M, et al. (2025) Double prenylation of budding yeast Ykt6 regulates cell wall integrity and autophagy. J Biol Chem 301(4):108384 PMID:40049413
- Wang Y, et al. (2018) The cellular economy of the Saccharomyces cerevisiae zinc proteome. Metallomics 10(12):1755-1776 PMID:30358795
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Witter DJ and Poulter CD (1996) Yeast geranylgeranyltransferase type-II: steady state kinetic studies of the recombinant enzyme. Biochemistry 35(32):10454-63 PMID:8756702
- Jiang Y, et al. (1995) Characterization of yeast type-II geranylgeranyltransferase. Methods Enzymol 257:21-9 PMID:8583924
- Jiang Y and Ferro-Novick S (1994) Identification of yeast component A: reconstitution of the geranylgeranyltransferase that modifies Ypt1p and Sec4p. Proc Natl Acad Sci U S A 91(10):4377-81 PMID:8183917
- Jiang Y, et al. (1993) Bet2p and Mad2p are components of a prenyltransferase that adds geranylgeranyl onto Ypt1p and Sec4p. Nature 366(6450):84-6 PMID:8232542
- Li R, et al. (1993) The mitotic feedback control gene MAD2 encodes the alpha-subunit of a prenyltransferase. Nature 366(6450):82-4 PMID:8232541
- Rossi G, et al. (1991) Dependence of Ypt1 and Sec4 membrane attachment on Bet2. Nature 351(6322):158-61 PMID:1903184
- Newman AP and Ferro-Novick S (1987) Characterization of new mutants in the early part of the yeast secretory pathway isolated by a [3H]mannose suicide selection. J Cell Biol 105(4):1587-94 PMID:3312234
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- O'Brien MJ and Ansari A (2024) Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle. Biochim Biophys Acta Proteins Proteom 1872(1):140968 PMID:37863410
- Cohen N, et al. (2023) A systematic proximity ligation approach to studying protein-substrate specificity identifies the substrate spectrum of the Ssh1 translocon. EMBO J 42(11):e113385 PMID:37073826
- Langemeyer L, et al. (2018) A guanine nucleotide exchange factor (GEF) limits Rab GTPase-driven membrane fusion. J Biol Chem 293(2):731-739 PMID:29184002
- Miller JE, et al. (2018) Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. G3 (Bethesda) 8(1):315-330 PMID:29158339
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Srivas R, et al. (2016) A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy. Mol Cell 63(3):514-25 PMID:27453043
- Steunou AL, et al. (2016) Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome. Mol Cell Biol 36(22):2768-2781 PMID:27550811
- van Leeuwen J, et al. (2016) Exploring genetic suppression interactions on a global scale. Science 354(6312) PMID:27811238
- Mitchell SF, et al. (2013) Global analysis of yeast mRNPs. Nat Struct Mol Biol 20(1):127-33 PMID:23222640
- van Pel DM, et al. (2013) Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. G3 (Bethesda) 3(2):273-82 PMID:23390603
- Willmund F, et al. (2013) The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell 152(1-2):196-209 PMID:23332755
- Chesi A, et al. (2012) The role of the Parkinson's disease gene PARK9 in essential cellular pathways and the manganese homeostasis network in yeast. PLoS One 7(3):e34178 PMID:22457822
- Schenk L, et al. (2012) La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast. RNA 18(3):449-61 PMID:22271760
- Hoppins S, et al. (2011) A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J Cell Biol 195(2):323-40 PMID:21987634
- Stirling PC, et al. (2011) The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components. PLoS Genet 7(4):e1002057 PMID:21552543
- Batisse J, et al. (2009) Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. J Biol Chem 284(50):34911-7 PMID:19840948
- Yu H, et al. (2008) High-quality binary protein interaction map of the yeast interactome network. Science 322(5898):104-10 PMID:18719252
- Dursina B, et al. (2002) Interaction of yeast Rab geranylgeranyl transferase with its protein and lipid substrates. Biochemistry 41(21):6805-16 PMID:12022885
- Gavin AC, et al. (2002) Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415(6868):141-7 PMID:11805826
- Ram RJ, et al. (2002) Identification of Sec36p, Sec37p, and Sec38p: components of yeast complex that contains Sec34p and Sec35p. Mol Biol Cell 13(5):1484-500 PMID:12006647
- Finger FP and Novick P (1997) Sec3p is involved in secretion and morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 8(4):647-62 PMID:9247645
- Witter DJ and Poulter CD (1996) Yeast geranylgeranyltransferase type-II: steady state kinetic studies of the recombinant enzyme. Biochemistry 35(32):10454-63 PMID:8756702
- Jiang Y and Ferro-Novick S (1994) Identification of yeast component A: reconstitution of the geranylgeranyltransferase that modifies Ypt1p and Sec4p. Proc Natl Acad Sci U S A 91(10):4377-81 PMID:8183917
- Li R, et al. (1993) The mitotic feedback control gene MAD2 encodes the alpha-subunit of a prenyltransferase. Nature 366(6450):82-4 PMID:8232541
- Stearns T, et al. (1990) ADP-ribosylation factor is functionally and physically associated with the Golgi complex. Proc Natl Acad Sci U S A 87(3):1238-42 PMID:2105501
- Bacon RA, et al. (1989) The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants. J Cell Biol 109(3):1015-22 PMID:2504726
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
Functional Complementation Annotations Literature
Paper(s) associated with one or more pieces of functional complementation annotations evidence in SGD.
No functional complementation annotations literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Herrero E, et al. (2020) Asymmetric Transcription Factor Partitioning During Yeast Cell Division Requires the FACT Chromatin Remodeler and Cell Cycle Progression. Genetics 216(3):701-716 PMID:32878900
- Hendry JA, et al. (2015) Leveraging DNA damage response signaling to identify yeast genes controlling genome stability. G3 (Bethesda) 5(5):997-1006 PMID:25721128
- Sukhai MA, et al. (2013) Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors. J Clin Invest 123(1):315-28 PMID:23202731
- van Pel DM, et al. (2013) Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. G3 (Bethesda) 3(2):273-82 PMID:23390603
- Pir P, et al. (2012) The genetic control of growth rate: a systems biology study in yeast. BMC Syst Biol 6:4 PMID:22244311
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Hu Z, et al. (2007) Genetic reconstruction of a functional transcriptional regulatory network. Nat Genet 39(5):683-7 PMID:17417638
- MacIsaac KD, et al. (2006) An improved map of conserved regulatory sites for Saccharomyces cerevisiae. BMC Bioinformatics 7:113 PMID:16522208
- Lum PY, et al. (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37 PMID:14718172
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549