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PIN3 / YPR154W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
LSB2 5
Feature Type
ORF , Verified
Description
Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with LSB1 cooperatively inhibits the nucleation of actin filaments; short-lived protein whose levels increase in response to thermal stress; induces the formation of the [PIN+] and [RNQ+] prions when overproduced; PIN3 has a paralog, LSB1, that arose from the whole genome duplication 1 2 3 4
Paralog
LSB1 3

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