CTR1 / YPR124W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant has a decreased rate of vegetative growth; null has a decreased respiratory growth rate that can be rescued by addition of copper sulfate; null mutant displays decreased utilization of various carbon and nitrogen sources and decreased competitive fitness on various carbon sources; null mutant has decreased resistance to various metals, oxidative stress, alkaline pH, desiccation and heat shock; haploinsufficiency results in elevated chromosome instability; homozygous null mutant has a decreased sporulation efficiency; overexpression can result in either inviability or reduced growth rate, abnormal cytoskeleton morphology, and alkaline pH resistance

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources