Literature Help
ISR1 / YPR106W Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Nishikawa A, et al. (2024) Ngk1 kinase-mediated N-acetylglucosamine metabolism promotes UDP-GlcNAc biosynthesis in Saccharomyces cerevisiae. FEBS Lett 598(13):1644-1654 PMID:38622055
- Alme EB, et al. (2020) The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae. PLoS Genet 16(6):e1008840 PMID:32579556
- Mehlgarten C, et al. (2007) Dosage suppression of the Kluyveromyces lactis zymocin by Saccharomyces cerevisiae ISR1 and UGP1. FEMS Yeast Res 7(5):722-30 PMID:17367514
- Miyahara K, et al. (1998) Functional interaction of Isr1, a predicted protein kinase, with the Pkc1 pathway in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 62(7):1376-80 PMID:9720220
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
Reset
Click on a gene or a paper to go to its specific page within SGD. Drag any of the gene or paper objects around
within the visualization for easier viewing and click “Reset” to automatically redraw the diagram.
Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Ostapenko D and Solomon MJ (2011) Anaphase promoting complex-dependent degradation of transcriptional repressors Nrm1 and Yhp1 in Saccharomyces cerevisiae. Mol Biol Cell 22(13):2175-84 PMID:21562221
- Ratnakumar S, et al. (2011) Phenomic and transcriptomic analyses reveal that autophagy plays a major role in desiccation tolerance in Saccharomyces cerevisiae. Mol Biosyst 7(1):139-49 PMID:20963216
- Miranda-Saavedra D and Barton GJ (2007) Classification and functional annotation of eukaryotic protein kinases. Proteins 68(4):893-914 PMID:17557329
- Miranda-Saavedra D, et al. (2007) The complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombe. BMC Genomics 8:309 PMID:17784954
- Brinkworth RI, et al. (2006) Protein kinases associated with the yeast phosphoproteome. BMC Bioinformatics 7:47 PMID:16445868
- Guo Y, et al. (2006) Analysis of cellular responses to aflatoxin B(1) in yeast expressing human cytochrome P450 1A2 using cDNA microarrays. Mutat Res 593(1-2):121-42 PMID:16122766
- Dephoure N, et al. (2005) Combining chemical genetics and proteomics to identify protein kinase substrates. Proc Natl Acad Sci U S A 102(50):17940-5 PMID:16330754
Reviews
No reviews curated.
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Nishikawa A, et al. (2024) Ngk1 kinase-mediated N-acetylglucosamine metabolism promotes UDP-GlcNAc biosynthesis in Saccharomyces cerevisiae. FEBS Lett 598(13):1644-1654 PMID:38622055
- Alme EB, et al. (2020) The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae. PLoS Genet 16(6):e1008840 PMID:32579556
- Mehlgarten C, et al. (2007) Dosage suppression of the Kluyveromyces lactis zymocin by Saccharomyces cerevisiae ISR1 and UGP1. FEMS Yeast Res 7(5):722-30 PMID:17367514
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Smurova K, et al. (2023) Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores. Nat Commun 14(1):3172 PMID:37263996
- Lu PYT, et al. (2022) A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans. Genetics 222(3) PMID:36066422
- Yang X, et al. (2022) The ubiquitin-proteasome system regulates meiotic chromosome organization. Proc Natl Acad Sci U S A 119(17):e2106902119 PMID:35439061
- Alme EB, et al. (2020) The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae. PLoS Genet 16(6):e1008840 PMID:32579556
- Sanders E, et al. (2020) Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1. G3 (Bethesda) 10(12):4359-4368 PMID:33115720
- Corcoles-Saez I, et al. (2018) Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein Homeostasis. Dev Cell 46(4):495-503.e2 PMID:30130531
- Kuzmin E, et al. (2018) Systematic analysis of complex genetic interactions. Science 360(6386) PMID:29674565
- Miller JE, et al. (2018) Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. G3 (Bethesda) 8(1):315-330 PMID:29158339
- Makrantoni V, et al. (2017) A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis. G3 (Bethesda) 7(9):3203-3215 PMID:28754723
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Mark KG, et al. (2014) Ubiquitin ligase trapping identifies an SCF(Saf1) pathway targeting unprocessed vacuolar/lysosomal proteins. Mol Cell 53(1):148-61 PMID:24389104
- Mitchell SF, et al. (2013) Global analysis of yeast mRNPs. Nat Struct Mol Biol 20(1):127-33 PMID:23222640
- Willmund F, et al. (2013) The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell 152(1-2):196-209 PMID:23332755
- Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801 PMID:22282571
- Fasolo J, et al. (2011) Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes. Genes Dev 25(7):767-78 PMID:21460040
- Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9 PMID:21127252
- Breitkreutz A, et al. (2010) A global protein kinase and phosphatase interaction network in yeast. Science 328(5981):1043-6 PMID:20489023
- Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31 PMID:20093466
- Vembar SS, et al. (2010) J domain co-chaperone specificity defines the role of BiP during protein translocation. J Biol Chem 285(29):22484-94 PMID:20430885
- Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63 PMID:19269370
- Holbein S, et al. (2009) Cordycepin interferes with 3' end formation in yeast independently of its potential to terminate RNA chain elongation. RNA 15(5):837-49 PMID:19324962
- Jonikas MC, et al. (2009) Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323(5922):1693-7 PMID:19325107
- Hasegawa Y, et al. (2008) Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. RNA 14(11):2333-47 PMID:18805955
- Tarassov K, et al. (2008) An in vivo map of the yeast protein interactome. Science 320(5882):1465-70 PMID:18467557
- Dephoure N, et al. (2005) Combining chemical genetics and proteomics to identify protein kinase substrates. Proc Natl Acad Sci U S A 102(50):17940-5 PMID:16330754
- Ito T, et al. (2001) A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc Natl Acad Sci U S A 98(8):4569-74 PMID:11283351
- Miyahara K, et al. (1998) Functional interaction of Isr1, a predicted protein kinase, with the Pkc1 pathway in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 62(7):1376-80 PMID:9720220
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Guan M, et al. (2023) Delving into the molecular initiating event of cadmium toxification via the dose-dependent functional genomics approach in Saccharomyces cerevisiae. Environ Pollut 323:121287 PMID:36791950
- Alme EB, et al. (2020) The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae. PLoS Genet 16(6):e1008840 PMID:32579556
- Guan M, et al. (2020) Molecular fingerprints of conazoles via functional genomic profiling of Saccharomyces cerevisiae. Toxicol In Vitro 69:104998 PMID:32919014
- Fletcher E, et al. (2019) Yeast chemogenomic screen identifies distinct metabolic pathways required to tolerate exposure to phenolic fermentation inhibitors ferulic acid, 4-hydroxybenzoic acid and coniferyl aldehyde. Metab Eng 52:98-109 PMID:30471359
- García R, et al. (2015) Genomic profiling of fungal cell wall-interfering compounds: identification of a common gene signature. BMC Genomics 16(1):683 PMID:26341223
- Hendry JA, et al. (2015) Leveraging DNA damage response signaling to identify yeast genes controlling genome stability. G3 (Bethesda) 5(5):997-1006 PMID:25721128
- Ostrow AZ, et al. (2014) Fkh1 and Fkh2 bind multiple chromosomal elements in the S. cerevisiae genome with distinct specificities and cell cycle dynamics. PLoS One 9(2):e87647 PMID:24504085
- VanderSluis B, et al. (2014) Broad metabolic sensitivity profiling of a prototrophic yeast deletion collection. Genome Biol 15(4):R64 PMID:24721214
- Gaytán BD, et al. (2013) A genome-wide screen identifies yeast genes required for tolerance to technical toxaphene, an organochlorinated pesticide mixture. PLoS One 8(11):e81253 PMID:24260565
- Gaytán BD, et al. (2013) Functional profiling discovers the dieldrin organochlorinated pesticide affects leucine availability in yeast. Toxicol Sci 132(2):347-58 PMID:23358190
- Michaillat L and Mayer A (2013) Identification of genes affecting vacuole membrane fragmentation in Saccharomyces cerevisiae. PLoS One 8(2):e54160 PMID:23383298
- Neumüller RA, et al. (2013) Conserved regulators of nucleolar size revealed by global phenotypic analyses. Sci Signal 6(289):ra70 PMID:23962978
- North M, et al. (2012) Genome-wide functional profiling identifies genes and processes important for zinc-limited growth of Saccharomyces cerevisiae. PLoS Genet 8(6):e1002699 PMID:22685415
- O'Connor ST, et al. (2012) Genome-Wide Functional and Stress Response Profiling Reveals Toxic Mechanism and Genes Required for Tolerance to Benzo[a]pyrene in S. cerevisiae. Front Genet 3:316 PMID:23403841
- Qian W, et al. (2012) The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast. Cell Rep 2(5):1399-410 PMID:23103169
- Ratnakumar S, et al. (2011) Phenomic and transcriptomic analyses reveal that autophagy plays a major role in desiccation tolerance in Saccharomyces cerevisiae. Mol Biosyst 7(1):139-49 PMID:20963216
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Alamgir M, et al. (2010) Chemical-genetic profile analysis of five inhibitory compounds in yeast. BMC Chem Biol 10:6 PMID:20691087
- Holbein S, et al. (2009) Cordycepin interferes with 3' end formation in yeast independently of its potential to terminate RNA chain elongation. RNA 15(5):837-49 PMID:19324962
- Yoshikawa K, et al. (2009) Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae. FEMS Yeast Res 9(1):32-44 PMID:19054128
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Cipollina C, et al. (2008) Saccharomyces cerevisiae SFP1: at the crossroads of central metabolism and ribosome biogenesis. Microbiology (Reading) 154(Pt 6):1686-1699 PMID:18524923
- Brown JA, et al. (2006) Global analysis of gene function in yeast by quantitative phenotypic profiling. Mol Syst Biol 2:2006.0001 PMID:16738548
- Deutschbauer AM, et al. (2005) Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast. Genetics 169(4):1915-25 PMID:15716499
- Lum PY, et al. (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37 PMID:14718172
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549
- Steinmetz LM, et al. (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4 PMID:12134146