Phenotype Help

RVB2 / YPL235W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

31 entries for 20 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
cell cycle progression in G1 phase: arrested
classical geneticsconditional
Allele: rvb2-(tih2-160)
S288CTemperature: elevated temperature, 37 °C
Lim CR, et al. (2000) PMID:10787406
cell size: decreased
heterozygous diploid, systematic mutation set

analysis of cell size for mutants in the systematic deletion collection

null
Allele: rvb2-Δ
S288CDetails: mutant is among the smallest 5% of heterozygous diploid deletion strains
Jorgensen P, et al. (2002) PMID:12089449
chemical compound excretion: increased
systematic mutation set

Dox titratable strains: Tet-regulated promoter that is shut off by the addition of doxycycline

repressibleS288C inositolDetails: Opi- phenotype; overproduction and excretion of inositol in the absence of inositol and choline
Salas-Santiago B and Lopes JM (2014) PMID:24558266
chromosome/plasmid maintenance: abnormal
large-scale surveyconditional
Allele: rvb2-ts
S288CAssay: a-like faker (ALF) assay
Temperature: semi-permissive temperature
Details: indicative of chromosome instability (CIN); metascore strong (multiple hit)
Stirling PC, et al. (2011) PMID:21552543
cold sensitivity: increased
classical geneticsreduction of function
Allele: rvb2-K81R
OtherTemperature: reduced temperature, 16 °C
King TH, et al. (2001) PMID:11604509
colony sectoring: increased
classical geneticsconditional
Allele: rvb2-ts
S288CAssay: chromosome transmission fidelity (CTF) assay
Temperature: elevated temperature, 30 °C - 37 °C
Details: indicative of chromosome instability (CIN); score severe
Ben-Aroya S, et al. (2010) PMID:20174551
competitive fitness: decreased
competitive growth

fitness profiling of essential genes using hypomorphic DAmP alleles

reduction of functionS288CMedia: minimal medium
Details: Relative fitness score: 0.929
Breslow DK, et al. (2008) PMID:18622397
competitive fitness: decreased
heterozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: rvb2-Δ
S288CMedia: YPD
Details: Relative fitness score: 0.926
Deutschbauer AM, et al. (2005) PMID:15716499
filamentous growth: increased
systematic mutation setnull
Allele: rvb2-Δ
Sigma1278bJin R, et al. (2008) PMID:17989363
flocculation: increased
heterozygous diploidnull
Allele: rvb2-Δ
OtherRadovic S, et al. (2007) PMID:17302941
Showing 1 to 10 of 31 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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