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ISU1 / YPL135W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
NUA1
Protein Product
iron-binding protein ISU1
Feature Type
ORF , Verified
Description
Conserved protein of the mitochondrial matrix; performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); ISU1 has a paralog, ISU2, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant 1 2 3 4 5 6
Paralog
ISU2 5

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