Phenotype Help

COX11 / YPL132W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene; null mutant is incapable of respiratory growth on nonfermentable carbon sources and grows slowly on fermentable carbon sources (petite phenotype); null mutant is also highly sensitive to oxidative stress caused by hydrogen peroxide and shows increased frequency of nonfunctional mitochondrial genome (rho- mutations); mutation within the copper binding site has no effect on oxidative stress resistance but still blocks respiratory growth; in systematic studies mutants exhibit reduced ability to form biofilms and show elevated chitin deposition

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

66 entries for 25 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
biofilm formation: decreased
systematic mutation setnull
Allele: cox11-Δ
S288CVandenbosch D, et al. (2013) PMID:24034557
chemical compound accumulation: decreased
homozygous diploid, systematic mutation set

glycogen accumulation in diploid mutant strains grown in microtiter plates

null
Allele: cox11-Δ
S288C glycogenWilson WA, et al. (2002) PMID:12096123
chemical compound excretion: increased
homozygous diploid, systematic mutation set

quantification of extracellular glutathione at stationary phase

null
Allele: cox11-Δ
S288C glutathioneTreatment: SD medium
Details: Fold elevation of glutathione excretion: 8
Perrone GG, et al. (2005) PMID:15509654
chitin deposition: increased
systematic mutation setnull
Allele: cox11-Δ
S288CDetails: Chitin level (nmole GlcNAc/mg dry weight): 20
Lesage G, et al. (2005) PMID:15715908
chronological lifespan: decreased
systematic mutation setnull
Allele: cox11-Δ
S288CMarek A and Korona R (2013) PMID:24151994
chronological lifespan: increased
systematic mutation set null
Allele: cox11-Δ
S288CCampos SE, et al. (2018) PMID:29575540
competitive fitness: decreased
systematic mutation setnull
Allele: cox11-Δ
S288C ethanolQian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: cox11-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: cox11-Δ
S288CMedia: rich medium (YPD) w/6% ethanol, ETH
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: cox11-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
Showing 1 to 10 of 66 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


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