Phenotype Help

SUV3 / YPL029W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene in reference strain S288C; null mutant fails to respire, exhibits mitochondrial genome instability, and is sensitive to hygromycin B; suv3-1 point mutant fails to respire but maintains the mitochondrial genome; in large-scale studies, null mutant shows small cell size, sensitivity to desiccation, reduced biofilm formation, shorter chronological lifespan, and resistance to miconazole; null mutation in the Sigma1278b genetic background blocks invasive growth and decreases filamentous growth; diploid homozygous null mutant is sensitive to heat and K. lactis zymocin

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

46 entries for 30 phenotypes


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PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
biofilm formation: decreased
systematic mutation setnull
Allele: suv3-Δ
S288CVandenbosch D, et al. (2013) PMID:24034557
cell size: decreased
systematic mutation set

analysis of cell size for mutants in the systematic deletion collection

null
Allele: suv3-Δ
S288CDetails: mutant is among the smallest 5% of haploid deletion strains
Jorgensen P, et al. (2002) PMID:12089449
chemical compound accumulation: abnormal
systematic mutation setnull
Allele: suv3-Δ
S288C alpha-amino acidDetails: Significantly altered free amino acid profile (X^2- test p < 0.01)
Mülleder M, et al. (2016) PMID:27693354
chemical compound accumulation: decreased
homozygous diploid, systematic mutation set

glycogen accumulation in diploid mutant strains grown in microtiter plates

null
Allele: suv3-Δ
S288C glycogenWilson WA, et al. (2002) PMID:12096123
chemical compound accumulation: decreased
systematic mutation setnull
Allele: suv3-Δ
S288C potassium(1+)Yu D, et al. (2012) PMID:23151179
chronological lifespan: decreased
systematic mutation setnull
Allele: suv3-Δ
S288CMarek A and Korona R (2013) PMID:24151994
competitive fitness: decreased
homozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: suv3-Δ
S288CMedia: YPD
Details: Relative fitness score: 0.832
Deutschbauer AM, et al. (2005) PMID:15716499
desiccation resistance: decreased
systematic mutation setnull
Allele: suv3-Δ
S288CDetails: less than 10% viability after dehydration stress
Rodríguez-Porrata B, et al. (2012) PMID:22181064
filamentous growth: decreased
systematic mutation setnull
Allele: suv3-Δ
Sigma1278bDetails: greatly decreased
Jin R, et al. (2008) PMID:17989363
heat sensitivity: increased
homozygous diploid, systematic mutation set

pooled screening for fitness defects at 37 deg C relative to 30 deg C

null
Allele: suv3-Δ
S288CTemperature: elevated temperature, 37 °C
Sinha H, et al. (2008) PMID:18780730
Showing 1 to 10 of 46 entries

Shared Phenotypes

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