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CTF19 / YPL018W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
MCM18
Feature Type
ORF , Verified
Description
Outer kinetochore protein, needed for accurate chromosome segregation; component of kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as platform for kinetochore assembly; required for spindle assembly checkpoint; minimizes potentially deleterious centromere-proximal crossovers by preventing meiotic DNA break formation proximal to centromere; homolog of human centromere constitutive-associated network (CCAN) subunit CENP-P and fission yeast fta2 1 2 3 5 6 7

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