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LDB19 / YOR322C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
ART1 2
Feature Type
ORF , Verified
Description
Alpha-arrestin involved in ubiquitin-dependent endocytosis; regulates endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its targets; involved in basal internalization and turnover of alpha-factor receptor Ste2p, and in mating and zygote formation; recruits ubiquitin ligase Rsp5p to Ste2p via its 2 PPXY motifs; inhibited by Npr1p-mediated phosphorylation, which affects translocation between cytosol and plasma membrane 1 2 3 4 5

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