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YPK9 / YOR291W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Protein Product
putative acid anhydride hydrolase
Feature Type
ORF , Verified
Description
Vacuolar protein with a possible role in sequestering heavy metals; involved in the oxidative stress response and modulation of replicative lifespan; undergoes autophosphorylation, which is abolished by mutation of Asp781 in the catalytic motif (D781N); P5 ATPase subfamily member with similarity to yeast Spf1p and homology of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor-Rakeb syndrome 1 2 3 4 5 6

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