Sequence Help

MOD5 / YOR274W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
[MOD+] 4
Protein Product
tRNA dimethylallyltransferase
Feature Type
ORF , Verified
Description
Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase; required for biosynthesis of isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; also has a role in tRNA gene-mediated silencing; gene encodes two isozymic forms; converts to a prion form, prion conversion contributes to azole antifungal resistance by upregulating ergosterol biosynthesis; homolog of human TRIT1, a mutation in which is associated with severe combined respiratory chain defects 1 2 3 4 5 6
EC Number
2.5.1.75

Resources