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MGE1 / YOR232W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
YGE1 3 , GRPE 2
Feature Type
ORF , Verified
Description
Mitochondrial matrix cochaperone; nucleotide release factor for Ssc1p in protein translocation and folding; also acts as cochaperone for Ssq1p in folding of Fe-S cluster proteins; acts as oxidative sensor to regulate mitochondrial Ssc1p; in presence of oxidative stress, dimeric Mge1p becomes a monomer and unable to regulate Ssc1p function; homolog of E. coli GrpE and human Mge1 (GRPEL1), which also responds to oxidative stress 1 2 3 4 5 6 7

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