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SKI7 / YOR076C Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Neto VG, et al. (2025) New insights into nuclear import and nucleolar localization of yeast RNA exosome subunits. Mol Biol Cell 36(6):ar69 PMID:40266794
- Keidel A, et al. (2023) Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Mol Cell 83(22):4093-4105.e7 PMID:37879335
- He F, et al. (2022) Dcp2 C-terminal cis-binding elements control selective targeting of the decapping enzyme by forming distinct decapping complexes. Elife 11 PMID:35604319
- Hurtig JE, et al. (2020) Origin, conservation, and loss of alternative splicing events that diversify the proteome in Saccharomycotina budding yeasts. RNA 26(10):1464-1480 PMID:32631843
- Zhang E, et al. (2019) A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes. EMBO J 38(14):e100640 PMID:31304628
- He F, et al. (2018) General decapping activators target different subsets of inefficiently translated mRNAs. Elife 7 PMID:30520724
- Jamar NH, et al. (2018) Loss of mRNA surveillance pathways results in widespread protein aggregation. Sci Rep 8(1):3894 PMID:29497115
- Marshall AN, et al. (2018) Conservation of mRNA quality control factor Ski7 and its diversification through changes in alternative splicing and gene duplication. Proc Natl Acad Sci U S A 115(29):E6808-E6816 PMID:29967155
- Kalisiak K, et al. (2017) A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans. Nucleic Acids Res 45(4):2068-2080 PMID:28204585
- Arakawa S, et al. (2016) Quality control of nonstop membrane proteins at the ER membrane and in the cytosol. Sci Rep 6:30795 PMID:27481473
- Horikawa W, et al. (2016) Mutations in the G-domain of Ski7 cause specific dysfunction in non-stop decay. Sci Rep 6:29295 PMID:27381255
- Huch S, et al. (2016) The decapping activator Edc3 and the Q/N-rich domain of Lsm4 function together to enhance mRNA stability and alter mRNA decay pathway dependence in Saccharomyces cerevisiae. Biol Open 5(10):1388-1399 PMID:27543059
- Kowalinski E, et al. (2016) Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex. Mol Cell 63(1):125-34 PMID:27345150
- Liu JJ, et al. (2016) CryoEM structure of yeast cytoplasmic exosome complex. Cell Res 26(7):822-37 PMID:27174052
- Mülleder M, et al. (2016) Functional Metabolomics Describes the Yeast Biosynthetic Regulome. Cell 167(2):553-565.e12 PMID:27693354
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Crowder JJ, et al. (2015) Rkr1/Ltn1 Ubiquitin Ligase-mediated Degradation of Translationally Stalled Endoplasmic Reticulum Proteins. J Biol Chem 290(30):18454-66 PMID:26055716
- Kowalinski E, et al. (2015) Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases. Structure 23(7):1336-43 PMID:26051716
- Shi Y, et al. (2015) A strategy for dissecting the architectures of native macromolecular assemblies. Nat Methods 12(12):1135-8 PMID:26436480
- Edwards MD, et al. (2014) Interactions between chromosomal and nonchromosomal elements reveal missing heritability. Proc Natl Acad Sci U S A 111(21):7719-22 PMID:24825890
- Lee JY, et al. (2014) Crystallization and preliminary X-ray analysis of the C-terminal fragment of Ski7 from Saccharomyces cerevisiae. Acta Crystallogr F Struct Biol Commun 70(Pt 9):1252-5 PMID:25195903
- Halbach F, et al. (2013) The yeast ski complex: crystal structure and RNA channeling to the exosome complex. Cell 154(4):814-26 PMID:23953113
- Letzring DP, et al. (2013) Translation of CGA codon repeats in yeast involves quality control components and ribosomal protein L1. RNA 19(9):1208-17 PMID:23825054
- Marshall AN, et al. (2013) Alternative splicing and subfunctionalization generates functional diversity in fungal proteomes. PLoS Genet 9(3):e1003376 PMID:23516382
- Zaborske JM, et al. (2013) Multiple transcripts from a 3'-UTR reporter vary in sensitivity to nonsense-mediated mRNA decay in Saccharomyces cerevisiae. PLoS One 8(11):e80981 PMID:24260526
- Pestov DG and Shcherbik N (2012) Rapid cytoplasmic turnover of yeast ribosomes in response to rapamycin inhibition of TOR. Mol Cell Biol 32(11):2135-44 PMID:22451491
- Tsuboi T, et al. (2012) Dom34:hbs1 plays a general role in quality-control systems by dissociation of a stalled ribosome at the 3' end of aberrant mRNA. Mol Cell 46(4):518-29 PMID:22503425
- Bregman A, et al. (2011) Promoter elements regulate cytoplasmic mRNA decay. Cell 147(7):1473-83 PMID:22196725
- Cole SE, et al. (2009) A convergence of rRNA and mRNA quality control pathways revealed by mechanistic analysis of nonfunctional rRNA decay. Mol Cell 34(4):440-50 PMID:19481524
- Synowsky SA, et al. (2009) Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes. J Mol Biol 385(4):1300-13 PMID:19046973
- Atkinson GC, et al. (2008) Evolution of nonstop, no-go and nonsense-mediated mRNA decay and their termination factor-derived components. BMC Evol Biol 8:290 PMID:18947425
- Meaux S, et al. (2008) Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly(A) tail. Mol Cell 29(1):134-40 PMID:18206975
- Thompson DM, et al. (2008) tRNA cleavage is a conserved response to oxidative stress in eukaryotes. RNA 14(10):2095-103 PMID:18719243
- Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 PMID:17660569
- Houalla R, et al. (2006) Microarray detection of novel nuclear RNA substrates for the exosome. Yeast 23(6):439-54 PMID:16652390
- Inada T and Aiba H (2005) Translation of aberrant mRNAs lacking a termination codon or with a shortened 3'-UTR is repressed after initiation in yeast. EMBO J 24(8):1584-95 PMID:15933721
- Wang L, et al. (2005) Domain interactions within the Ski2/3/8 complex and between the Ski complex and Ski7p. RNA 11(8):1291-302 PMID:16043509
- Mitchell P and Tollervey D (2003) An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation. Mol Cell 11(5):1405-13 PMID:12769863
- Takahashi S, et al. (2003) Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeast. EMBO J 22(15):3951-9 PMID:12881429
- Aloy P, et al. (2002) A complex prediction: three-dimensional model of the yeast exosome. EMBO Rep 3(7):628-35 PMID:12101094
- van Hoof A, et al. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295(5563):2262-4 PMID:11910110
- Araki Y, et al. (2001) Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast. EMBO J 20(17):4684-93 PMID:11532933
- He W and Parker R (2001) The yeast cytoplasmic LsmI/Pat1p complex protects mRNA 3' termini from partial degradation. Genetics 158(4):1445-55 PMID:11514438
- van Hoof A, et al. (2000) Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA. Mol Cell Biol 20(21):8230-43 PMID:11027292
- Benard L, et al. (1999) The ski7 antiviral protein is an EF1-alpha homolog that blocks expression of non-Poly(A) mRNA in Saccharomyces cerevisiae. J Virol 73(4):2893-900 PMID:10074137
- Ridley SP, et al. (1984) Superkiller mutations in Saccharomyces cerevisiae suppress exclusion of M2 double-stranded RNA by L-A-HN and confer cold sensitivity in the presence of M and L-A-HN. Mol Cell Biol 4(4):761-70 PMID:6371496
Related Literature
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Rudowitz M, et al. (2023) Utilization of Nonstop mRNA to Assess Ribosome-Associated Nascent Polypeptide Chains in Early Topogenesis of Peroxisomal Proteins. Methods Mol Biol 2643:383-390 PMID:36952200
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Kuzmin E, et al. (2020) Exploring whole-genome duplicate gene retention with complex genetic interaction analysis. Science 368(6498) PMID:32586993
- Brunkard JO and Baker B (2018) A Two-Headed Monster to Avert Disaster: HBS1/SKI7 Is Alternatively Spliced to Build Eukaryotic RNA Surveillance Complexes. Front Plant Sci 9:1333 PMID:30258456
- Chiabudini M, et al. (2014) Release factor eRF3 mediates premature translation termination on polylysine-stalled ribosomes in Saccharomyces cerevisiae. Mol Cell Biol 34(21):4062-76 PMID:25154418
- Shukla S and Parker R (2014) Quality control of assembly-defective U1 snRNAs by decapping and 5'-to-3' exonucleolytic digestion. Proc Natl Acad Sci U S A 111(32):E3277-86 PMID:25071210
- Soria PS, et al. (2014) Functional divergence for every paralog. Mol Biol Evol 31(4):984-92 PMID:24451325
- Defenouillère Q, et al. (2013) Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products. Proc Natl Acad Sci U S A 110(13):5046-51 PMID:23479637
- Chiabudini M, et al. (2012) Ribosome-associated complex and Ssb are required for translational repression induced by polylysine segments within nascent chains. Mol Cell Biol 32(23):4769-79 PMID:23007158
- Izawa T, et al. (2012) Roles of dom34:hbs1 in nonstop protein clearance from translocators for normal organelle protein influx. Cell Rep 2(3):447-53 PMID:22981232
- Lavoie M, et al. (2012) Regulation of conditional gene expression by coupled transcription repression and RNA degradation. Nucleic Acids Res 40(2):871-83 PMID:21933814
- Addinall SG, et al. (2011) Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects. PLoS Genet 7(4):e1001362 PMID:21490951
- Bendaha H, et al. (2011) New azole antifungal agents with novel modes of action: synthesis and biological studies of new tridentate ligands based on pyrazole and triazole. Eur J Med Chem 46(9):4117-24 PMID:21723647
- Chandramouli P, et al. (2011) Validation of the orthogonal tilt reconstruction method with a biological test sample. J Struct Biol 175(1):85-96 PMID:21536134
- Ramírez-Garrastacho M and Esteban R (2011) Yeast RNA viruses as indicators of exosome activity: human exosome hCsl4p participates in RNA degradation in Saccharomyces cerevisiae'. Yeast 28(12):821-32 PMID:22068837
- Schaeffer D and van Hoof A (2011) Different nuclease requirements for exosome-mediated degradation of normal and nonstop mRNAs. Proc Natl Acad Sci U S A 108(6):2366-71 PMID:21262801
- Tang X, et al. (2011) A comparison of the functional modules identified from time course and static PPI network data. BMC Bioinformatics 12:339 PMID:21849017
- Bengtson MH and Joazeiro CA (2010) Role of a ribosome-associated E3 ubiquitin ligase in protein quality control. Nature 467(7314):470-3 PMID:20835226
- Dowell RD, et al. (2010) Genotype to phenotype: a complex problem. Science 328(5977):469 PMID:20413493
- Mauchi N, et al. (2010) Stability control of MTL1 mRNA by the RNA-binding protein Khd1p in yeast. Cell Struct Funct 35(2):95-105 PMID:20953064
- Fujii K, et al. (2009) A role for ubiquitin in the clearance of nonfunctional rRNAs. Genes Dev 23(8):963-74 PMID:19390089
- Passos DO, et al. (2009) Analysis of Dom34 and its function in no-go decay. Mol Biol Cell 20(13):3025-32 PMID:19420139
- Pertschy B, et al. (2009) RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem 284(50):35079-91 PMID:19801658
- Gandhi R, et al. (2008) Depurination of Brome mosaic virus RNA3 in vivo results in translation-dependent accelerated degradation of the viral RNA. J Biol Chem 283(47):32218-28 PMID:18815133
- Mroczek S and Kufel J (2008) Apoptotic signals induce specific degradation of ribosomal RNA in yeast. Nucleic Acids Res 36(9):2874-88 PMID:18385160
- Dziembowski A, et al. (2007) A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nat Struct Mol Biol 14(1):15-22 PMID:17173052
- Doma MK and Parker R (2006) Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation. Nature 440(7083):561-4 PMID:16554824
- Goldstrohm AC, et al. (2006) PUF proteins bind Pop2p to regulate messenger RNAs. Nat Struct Mol Biol 13(6):533-9 PMID:16715093
- Meaux S and Van Hoof A (2006) Yeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly(A) tail in translation and mRNA decay. RNA 12(7):1323-37 PMID:16714281
- Burckin T, et al. (2005) Exploring functional relationships between components of the gene expression machinery. Nat Struct Mol Biol 12(2):175-82 PMID:15702072
- Muhlrad D and Parker R (2005) The yeast EDC1 mRNA undergoes deadenylation-independent decapping stimulated by Not2p, Not4p, and Not5p. EMBO J 24(5):1033-45 PMID:15706350
- Wilson MA, et al. (2005) Genetic interactions between [PSI+] and nonstop mRNA decay affect phenotypic variation. Proc Natl Acad Sci U S A 102(29):10244-9 PMID:16002465
- van Hoof A (2005) Conserved functions of yeast genes support the duplication, degeneration and complementation model for gene duplication. Genetics 171(4):1455-61 PMID:15965245
- Kellis M, et al. (2004) Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae. Nature 428(6983):617-24 PMID:15004568
- Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13 PMID:14764870
- Kushner DB, et al. (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9 PMID:14671320
- Sheth U and Parker R (2003) Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300(5620):805-8 PMID:12730603
- Maquat LE (2002) Molecular biology. Skiing toward nonstop mRNA decay. Science 295(5563):2221-2 PMID:11910094
- Brown JT, et al. (2000) The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo. RNA 6(3):449-57 PMID:10744028
- Searfoss AM and Wickner RB (2000) 3' poly(A) is dispensable for translation. Proc Natl Acad Sci U S A 97(16):9133-7 PMID:10922069
- Peltz SW, et al. (1999) Ribosomal protein L3 mutants alter translational fidelity and promote rapid loss of the yeast killer virus. Mol Cell Biol 19(1):384-91 PMID:9858562
- Valens M, et al. (1997) The sequence of a 54.7 kb fragment of yeast chromosome XV reveals the presence of two tRNAs and 24 new open reading frames. Yeast 13(4):379-90 PMID:9133743
- Ball SG, et al. (1984) Genetic Control of L-a and L-(Bc) Dsrna Copy Number in Killer Systems of SACCHAROMYCES CEREVISIAE. Genetics 107(2):199-217 PMID:17246214
Reviews
No reviews curated.
Download References (.nbib)
- Alagar Boopathy LR, et al. (2023) Proteostasis regulation through ribosome quality control and no-go-decay. Wiley Interdiscip Rev RNA 14(6):e1809 PMID:37488089
- Kazibwe Z, et al. (2019) The Ins and Outs of Autophagic Ribosome Turnover. Cells 8(12) PMID:31835634
- Wickner RB (2019) Genetics is the logic of life (at least of mine). FEMS Yeast Res 19(1) PMID:30329039
- Chlebowski A, et al. (2013) RNA decay machines: the exosome. Biochim Biophys Acta 1829(6-7):552-60 PMID:23352926
- Das S and Das B (2013) mRNA quality control pathways in Saccharomyces cerevisiae. J Biosci 38(3):615-40 PMID:23938393
- Inada T (2013) Quality control systems for aberrant mRNAs induced by aberrant translation elongation and termination. Biochim Biophys Acta 1829(6-7):634-42 PMID:23416749
- Wickner RB, et al. (2013) Viruses and prions of Saccharomyces cerevisiae. Adv Virus Res 86:1-36 PMID:23498901
- Parker R (2012) RNA degradation in Saccharomyces cerevisae. Genetics 191(3):671-702 PMID:22785621
- Shoemaker CJ and Green R (2012) Translation drives mRNA quality control. Nat Struct Mol Biol 19(6):594-601 PMID:22664987
- Schaeffer D, et al. (2011) Functions of the cytoplasmic exosome. Adv Exp Med Biol 702:79-90 PMID:21713679
- Schaeffer D, et al. (2010) Functions of the cytoplasmic exosome. Adv Exp Med Biol 702:79-90 PMID:21618876
- Lykke-Andersen S, et al. (2009) Origins and activities of the eukaryotic exosome. J Cell Sci 122(Pt 10):1487-94 PMID:19420235
- Feldbrügge M, et al. (2008) The posttranscriptional machinery of Ustilago maydis. Fungal Genet Biol 45 Suppl 1:S40-6 PMID:18468465
- Lebreton A and Séraphin B (2008) Exosome-mediated quality control: substrate recruitment and molecular activity. Biochim Biophys Acta 1779(9):558-65 PMID:18313413
- Mühlemann O, et al. (2008) Recognition and elimination of nonsense mRNA. Biochim Biophys Acta 1779(9):538-49 PMID:18657639
- Wilson MA, et al. (2008) Diverse aberrancies target yeast mRNAs to cytoplasmic mRNA surveillance pathways. Biochim Biophys Acta 1779(9):550-7 PMID:18554525
- Isken O and Maquat LE (2007) Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function. Genes Dev 21(15):1833-56 PMID:17671086
- Büttner K, et al. (2006) The exosome: a macromolecular cage for controlled RNA degradation. Mol Microbiol 61(6):1372-9 PMID:16968219
- Houseley J, et al. (2006) RNA-quality control by the exosome. Nat Rev Mol Cell Biol 7(7):529-39 PMID:16829983
- Lorentzen E and Conti E (2006) The exosome and the proteasome: nano-compartments for degradation. Cell 125(4):651-4 PMID:16713559
- Raijmakers R, et al. (2004) The exosome, a molecular machine for controlled RNA degradation in both nucleus and cytoplasm. Eur J Cell Biol 83(5):175-83 PMID:15346807
- Vasudevan S, et al. (2002) Non-stop decay--a new mRNA surveillance pathway. Bioessays 24(9):785-8 PMID:12210514
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Arakawa S, et al. (2016) Quality control of nonstop membrane proteins at the ER membrane and in the cytosol. Sci Rep 6:30795 PMID:27481473
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Kowalinski E, et al. (2015) Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases. Structure 23(7):1336-43 PMID:26051716
- Cole SE, et al. (2009) A convergence of rRNA and mRNA quality control pathways revealed by mechanistic analysis of nonfunctional rRNA decay. Mol Cell 34(4):440-50 PMID:19481524
- Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 PMID:17660569
- Mitchell P and Tollervey D (2003) An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation. Mol Cell 11(5):1405-13 PMID:12769863
- Takahashi S, et al. (2003) Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeast. EMBO J 22(15):3951-9 PMID:12881429
- van Hoof A, et al. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295(5563):2262-4 PMID:11910110
- Araki Y, et al. (2001) Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast. EMBO J 20(17):4684-93 PMID:11532933
- van Hoof A, et al. (2000) Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA. Mol Cell Biol 20(21):8230-43 PMID:11027292
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Meaux S, et al. (2008) Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly(A) tail. Mol Cell 29(1):134-40 PMID:18206975
- Inada T and Aiba H (2005) Translation of aberrant mRNAs lacking a termination codon or with a shortened 3'-UTR is repressed after initiation in yeast. EMBO J 24(8):1584-95 PMID:15933721
- Takahashi S, et al. (2003) Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeast. EMBO J 22(15):3951-9 PMID:12881429
- van Hoof A, et al. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295(5563):2262-4 PMID:11910110
- Benard L, et al. (1999) The ski7 antiviral protein is an EF1-alpha homolog that blocks expression of non-Poly(A) mRNA in Saccharomyces cerevisiae. J Virol 73(4):2893-900 PMID:10074137
- Ridley SP, et al. (1984) Superkiller mutations in Saccharomyces cerevisiae suppress exclusion of M2 double-stranded RNA by L-A-HN and confer cold sensitivity in the presence of M and L-A-HN. Mol Cell Biol 4(4):761-70 PMID:6371496
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- O'Brien MJ and Ansari A (2024) Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle. Biochim Biophys Acta Proteins Proteom 1872(1):140968 PMID:37863410
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Garcia I, et al. (2021) Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway. Cell Rep 37(13):110186 PMID:34965431
- Nsamba ET, et al. (2021) Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis. J Cell Biol 220(12) PMID:34739032
- Gotor NL, et al. (2020) RNA-binding and prion domains: the Yin and Yang of phase separation. Nucleic Acids Res 48(17):9491-9504 PMID:32857852
- Cepeda LPP, et al. (2019) The ribosome assembly factor Nop53 controls association of the RNA exosome with pre-60S particles in yeast. J Biol Chem 294(50):19365-19380 PMID:31662437
- Ciftci-Yilmaz S, et al. (2018) A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A. Genetics 210(1):203-218 PMID:30012561
- Miller JE, et al. (2018) Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. G3 (Bethesda) 8(1):315-330 PMID:29158339
- Falk S, et al. (2017) Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase. Cell Rep 20(10):2279-2286 PMID:28877463
- Jamar NH, et al. (2017) The non-stop decay mRNA surveillance pathway is required for oxidative stress tolerance. Nucleic Acids Res 45(11):6881-6893 PMID:28472342
- Jungfleisch J, et al. (2017) A novel translational control mechanism involving RNA structures within coding sequences. Genome Res 27(1):95-106 PMID:27821408
- Limoncelli KA, et al. (2017) ASC1 and RPS3: new actors in 18S nonfunctional rRNA decay. RNA 23(12):1946-1960 PMID:28956756
- Makrantoni V, et al. (2017) A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis. G3 (Bethesda) 7(9):3203-3215 PMID:28754723
- Arakawa S, et al. (2016) Quality control of nonstop membrane proteins at the ER membrane and in the cytosol. Sci Rep 6:30795 PMID:27481473
- Babour A, et al. (2016) The Chromatin Remodeler ISW1 Is a Quality Control Factor that Surveys Nuclear mRNP Biogenesis. Cell 167(5):1201-1214.e15 PMID:27863241
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Horikawa W, et al. (2016) Mutations in the G-domain of Ski7 cause specific dysfunction in non-stop decay. Sci Rep 6:29295 PMID:27381255
- Kowalinski E, et al. (2016) Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex. Mol Cell 63(1):125-34 PMID:27345150
- Liu JJ, et al. (2016) CryoEM structure of yeast cytoplasmic exosome complex. Cell Res 26(7):822-37 PMID:27174052
- Preissler S, et al. (2015) Not4-dependent translational repression is important for cellular protein homeostasis in yeast. EMBO J 34(14):1905-24 PMID:25971775
- Frenk S, et al. (2014) The nuclear exosome is active and important during budding yeast meiosis. PLoS One 9(9):e107648 PMID:25210768
- Halbach F, et al. (2013) The yeast ski complex: crystal structure and RNA channeling to the exosome complex. Cell 154(4):814-26 PMID:23953113
- Chiabudini M, et al. (2012) Ribosome-associated complex and Ssb are required for translational repression induced by polylysine segments within nascent chains. Mol Cell Biol 32(23):4769-79 PMID:23007158
- Halbach F, et al. (2012) The crystal structure of S. cerevisiae Ski2, a DExH helicase associated with the cytoplasmic functions of the exosome. RNA 18(1):124-34 PMID:22114319
- Izawa T, et al. (2012) Roles of dom34:hbs1 in nonstop protein clearance from translocators for normal organelle protein influx. Cell Rep 2(3):447-53 PMID:22981232
- Louie RJ, et al. (2012) A yeast phenomic model for the gene interaction network modulating CFTR-ΔF508 protein biogenesis. Genome Med 4(12):103 PMID:23270647
- Moehle EA, et al. (2012) The yeast SR-like protein Npl3 links chromatin modification to mRNA processing. PLoS Genet 8(11):e1003101 PMID:23209445
- Schaeffer D, et al. (2012) The CR3 motif of Rrp44p is important for interaction with the core exosome and exosome function. Nucleic Acids Res 40(18):9298-307 PMID:22833611
- Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801 PMID:22282571
- Finch AJ, et al. (2011) Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev 25(9):917-29 PMID:21536732
- León Ortiz AM, et al. (2011) Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions. DNA Repair (Amst) 10(5):506-17 PMID:21459050
- Schaeffer D and van Hoof A (2011) Different nuclease requirements for exosome-mediated degradation of normal and nonstop mRNAs. Proc Natl Acad Sci U S A 108(6):2366-71 PMID:21262801
- Bengtson MH and Joazeiro CA (2010) Role of a ribosome-associated E3 ubiquitin ligase in protein quality control. Nature 467(7314):470-3 PMID:20835226
- Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31 PMID:20093466
- Greenland KB, et al. (2010) Identification of Saccharomyces cerevisiae spindle pole body remodeling factors. PLoS One 5(11):e15426 PMID:21103054
- Michelot A, et al. (2010) Reconstitution and protein composition analysis of endocytic actin patches. Curr Biol 20(21):1890-9 PMID:21035341
- Batisse J, et al. (2009) Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. J Biol Chem 284(50):34911-7 PMID:19840948
- Cole SE, et al. (2009) A convergence of rRNA and mRNA quality control pathways revealed by mechanistic analysis of nonfunctional rRNA decay. Mol Cell 34(4):440-50 PMID:19481524
- Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63 PMID:19269370
- Synowsky SA, et al. (2009) Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes. J Mol Biol 385(4):1300-13 PMID:19046973
- Tonikian R, et al. (2009) Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins. PLoS Biol 7(10):e1000218 PMID:19841731
- Addinall SG, et al. (2008) A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae. Genetics 180(4):2251-66 PMID:18845848
- Hasegawa Y, et al. (2008) Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. RNA 14(11):2333-47 PMID:18805955
- Tarassov K, et al. (2008) An in vivo map of the yeast protein interactome. Science 320(5882):1465-70 PMID:18467557
- Wilmes GM, et al. (2008) A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell 32(5):735-46 PMID:19061648
- Dziembowski A, et al. (2007) A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nat Struct Mol Biol 14(1):15-22 PMID:17173052
- McClellan AJ, et al. (2007) Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches. Cell 131(1):121-35 PMID:17923092
- Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 PMID:17660569
- Gavin AC, et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature 440(7084):631-6 PMID:16429126
- Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43 PMID:16554755
- Synowsky SA, et al. (2006) Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex. Mol Cell Proteomics 5(9):1581-92 PMID:16829593
- Wang L, et al. (2005) Domain interactions within the Ski2/3/8 complex and between the Ski complex and Ski7p. RNA 11(8):1291-302 PMID:16043509
- Wilson MA, et al. (2005) Genetic interactions between [PSI+] and nonstop mRNA decay affect phenotypic variation. Proc Natl Acad Sci U S A 102(29):10244-9 PMID:16002465
- Krogan NJ, et al. (2004) High-definition macromolecular composition of yeast RNA-processing complexes. Mol Cell 13(2):225-39 PMID:14759368
- Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13 PMID:14764870
- Mitchell P, et al. (2003) Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs. Mol Cell Biol 23(19):6982-92 PMID:12972615
- Peng WT, et al. (2003) A panoramic view of yeast noncoding RNA processing. Cell 113(7):919-33 PMID:12837249
- Takahashi S, et al. (2003) Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeast. EMBO J 22(15):3951-9 PMID:12881429
- Gavin AC, et al. (2002) Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415(6868):141-7 PMID:11805826
- Tong AH, et al. (2002) A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science 295(5553):321-4 PMID:11743162
- Araki Y, et al. (2001) Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast. EMBO J 20(17):4684-93 PMID:11532933
- Fromont-Racine M, et al. (2000) Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins. Yeast 17(2):95-110 PMID:10900456
- van Hoof A, et al. (2000) Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA. Mol Cell Biol 20(21):8230-43 PMID:11027292
- Benard L, et al. (1999) The ski7 antiviral protein is an EF1-alpha homolog that blocks expression of non-Poly(A) mRNA in Saccharomyces cerevisiae. J Virol 73(4):2893-900 PMID:10074137
- Fromont-Racine M, et al. (1997) Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens. Nat Genet 16(3):277-82 PMID:9207794
- Ridley SP, et al. (1984) Superkiller mutations in Saccharomyces cerevisiae suppress exclusion of M2 double-stranded RNA by L-A-HN and confer cold sensitivity in the presence of M and L-A-HN. Mol Cell Biol 4(4):761-70 PMID:6371496
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
Download References (.nbib)
- Leutert M, et al. (2023) The regulatory landscape of the yeast phosphoproteome. Nat Struct Mol Biol 30(11):1761-1773 PMID:37845410
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- MacGilvray ME, et al. (2020) Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses. J Proteome Res 19(8):3405-3417 PMID:32597660
- Synowsky SA, et al. (2009) Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes. J Mol Biol 385(4):1300-13 PMID:19046973
- Albuquerque CP, et al. (2008) A multidimensional chromatography technology for in-depth phosphoproteome analysis. Mol Cell Proteomics 7(7):1389-96 PMID:18407956
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Jin X, et al. (2021) Retromer Complex and PI3K Complex II-Related Genes Mediate the Yeast (Saccharomyces cerevisiae) Sodium Metabisulfite Resistance Response. Cells 10(12) PMID:34944020
- Lao JP, et al. (2018) The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1. G3 (Bethesda) 8(12):3931-3944 PMID:30377154
- Mülleder M, et al. (2016) Functional Metabolomics Describes the Yeast Biosynthetic Regulome. Cell 167(2):553-565.e12 PMID:27693354
- North M, et al. (2016) Functional Toxicogenomic Profiling Expands Insight into Modulators of Formaldehyde Toxicity in Yeast. Front Genet 7:200 PMID:27909446
- Garay E, et al. (2014) High-resolution profiling of stationary-phase survival reveals yeast longevity factors and their genetic interactions. PLoS Genet 10(2):e1004168 PMID:24586198
- Gaupel AC, et al. (2014) High throughput screening identifies modulators of histone deacetylase inhibitors. BMC Genomics 15(1):528 PMID:24968945
- Ostrow AZ, et al. (2014) Fkh1 and Fkh2 bind multiple chromosomal elements in the S. cerevisiae genome with distinct specificities and cell cycle dynamics. PLoS One 9(2):e87647 PMID:24504085
- North M, et al. (2012) Genome-wide functional profiling identifies genes and processes important for zinc-limited growth of Saccharomyces cerevisiae. PLoS Genet 8(6):e1002699 PMID:22685415
- Pimentel C, et al. (2012) The role of the Yap5 transcription factor in remodeling gene expression in response to Fe bioavailability. PLoS One 7(5):e37434 PMID:22616008
- Pir P, et al. (2012) The genetic control of growth rate: a systems biology study in yeast. BMC Syst Biol 6:4 PMID:22244311
- Qian W, et al. (2012) The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast. Cell Rep 2(5):1399-410 PMID:23103169
- Hoon S, et al. (2011) A global perspective of the genetic basis for carbonyl stress resistance. G3 (Bethesda) 1(3):219-31 PMID:22384333
- Shi Y, et al. (2011) Two novel WD40 domain-containing proteins, Ere1 and Ere2, function in the retromer-mediated endosomal recycling pathway. Mol Biol Cell 22(21):4093-107 PMID:21880895
- Teng X, et al. (2011) Gene-dependent cell death in yeast. Cell Death Dis 2(8):e188 PMID:21814286
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Yadav V, et al. (2011) Chlorophenol stress affects aromatic amino acid biosynthesis-a genome-wide study. Yeast 28(1):81-91 PMID:20967895
- Alamgir M, et al. (2010) Chemical-genetic profile analysis of five inhibitory compounds in yeast. BMC Chem Biol 10:6 PMID:20691087
- Dowell RD, et al. (2010) Genotype to phenotype: a complex problem. Science 328(5977):469 PMID:20413493
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Hu Z, et al. (2007) Genetic reconstruction of a functional transcriptional regulatory network. Nat Genet 39(5):683-7 PMID:17417638
- Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 PMID:17660569
- Brown JA, et al. (2006) Global analysis of gene function in yeast by quantitative phenotypic profiling. Mol Syst Biol 2:2006.0001 PMID:16738548
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549