ASE1 / YOR058C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

ASE1/YOR058C is a non-essential gene; null mutants are viable and have abnormal spindle morphology, defects in cytokinesis, shortened chronological lifespan, decreased competitive fitness in rich medium, and increased sensitivity to mutliple chemicals, including amitrole, bleomycin, caffeine, camptothecin, and fluconazole; overexpression leads to delayed cell cycle passage through the metaphase-anaphase transition

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

45 entries for 22 phenotypes

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources