Sequence Help

WHI2 / YOR043W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

Feature Type
ORF , Verified
Negative regulator of TORC1 in response to limiting leucine; suppresses TORC1 activity with binding partners Psr1p/Psr2p, acting in parallel with SEACIT; regulates cell cycle arrest in stationary phase; inhibits Ras-cAMP-PKA regulation of apoptosis during nutrient depletion; required with Psr1p for activation of the general stress response; role in rapamycin-induced mitophagy; localizes to the cell periphery; human tumor suppressor and Whi2-like protein KCTD11 functionally complements the null 2 3 4 6 7 8 9