Sequence Help
CUE5 / YOR042W Sequence
Sequences and genome annotation information for Reference Strain S288C and a select set of
Alternative References.
- Protein Product
-
ubiquitin-binding protein CUE5
- Feature Type
- ORF
, Verified
- Description
-
Ubiquitin-binding protein; functions as ubiquitin-Atg8p adaptor in ubiquitin-dependent autophagy; serves as proteaphagy receptor for inactivated 26S proteasomes; contains CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; CUE5 has a paralog, DON1, that arose from the whole genome duplication; human TOLLIP is a functional CUE-domain homolog, can complement yeast null mutant, rescuing hypersensitivity of cue5 null mutant cells to Htt-96Q
1
2
3
5
6
- Paralog
-
DON1
5