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CDC33 / YOL139C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

TIF45 , eIF4E 6
Protein Product
translation initiation factor eIF4E
Feature Type
ORF , Verified
Translation initiation factor eIF4E; mRNA cap binding protein and subunit of the mRNA cap-binding complex (eIF4F) along with eIF4A (Tif1p/Tif2p) and eIF4G (Tif4631p/Tif4632p), that mediates cap-dependent translation; required with eIF4G for Ded1p-mediated stimulation of mRNA recruitment during 48S preinitiation complex (PIC) assembly; protein abundance increases in response to DNA replication stress; human homolog EIF4E can complement the cdc33 null mutant 2 3 4 5