Phenotype Help

BIO5 / YNR056C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene; null mutant displays decreased competitive fitness in minimal medium; null mutant has reduced starvation resistance; null mutant displays increased sensitivity to the biotin vitamers 7,8-diaminopelargonic acid and 7-keto-8-aminopelargonic; heterozygous null mutant is haploproficient

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

7 entries for 5 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: bio5-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.999
Breslow DK, et al. (2008) PMID:18622397
haploproficient
heterozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: bio5-Δ
S288CMedia: turbidostat growth in FPM medium
Details: Relative growth score: 0.0081
Pir P, et al. (2012) PMID:22244311
resistance to chemicals: decreased
systematic mutation setnull
Allele: bio5-Δ
S288C1.5 mM BAPTAYadav J, et al. (2007) PMID:17314395
resistance to chemicals: decreased
classical geneticsnull
Allele: bio5-Δ
Other25 ng/ml 8-amino-7-oxononanoic acidPhalip V, et al. (1999) PMID:10333520
resistance to chemicals: decreased
classical geneticsnull
Allele: bio5-Δ
Other5 ng/ml 7,8-diaminononanoic acidPhalip V, et al. (1999) PMID:10333520
starvation resistance: decreased
heterozygous diploid, competitive growth

pooled mutant strains were subjected to low nutrient stress, then dead cells were separated and their mutations identified

null
Allele: bio5-Δ
S288CDavey HM, et al. (2012) PMID:22356628
viable
systematic mutation setnull
Allele: bio5-Δ
S288CGiaever G, et al. (2002) PMID:12140549
Showing 1 to 7 of 7 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


Resources