Phenotype Help

DDI2 / YNL335W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene in reference strain S288C; null mutant is highly sensitive to cyanamide and MMS; in systematic studies mutants display increased biofilm formation and increased sensitivity to heat, hyperosmotic stress and elevated ethanol

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

13 entries for 8 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
biofilm formation: increased
systematic mutation setnull
Allele: ddi3-Δ
S288CVandenbosch D, et al. (2013) PMID:24034557
competitive fitness: increased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: ddi3-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 1.003
Breslow DK, et al. (2008) PMID:18622397
haploinsufficient
heterozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: ddi3-Δ
S288CMedia: turbidostat growth in FPM medium
Details: Relative growth score: -0.0059
Pir P, et al. (2012) PMID:22244311
haploinsufficient
heterozygous diploid, competitive growthnull
Allele: ddi3-Δ
S288CTreatment: conditions that mimic Phase II of a batch fermentation, equivalent to ~22 hours after inoculation of a batch fermentation
Novo M, et al. (2013) PMID:24040173
heat sensitivity: increased
systematic mutation setnull
Allele: ddi3-Δ
S288CTemperature: elevated temperature, 37 °C
Auesukaree C, et al. (2009) PMID:19638689
hyperosmotic stress resistance: decreased
systematic mutation setnull
Allele: ddi3-Δ
S288C1 M sodium chlorideYoshikawa K, et al. (2009) PMID:19054128
resistance to chemicals: decreased
systematic mutation setnull
Allele: ddi3-Δ
S288C8% ethanolYoshikawa K, et al. (2009) PMID:19054128
resistance to chemicals: decreased
systematic mutation setnull
Allele: ddi3-Δ
S288C7% propan-1-olAuesukaree C, et al. (2009) PMID:19638689
resistance to chemicals: decreased
homozygous diploid, systematic mutation setnull
Allele: ddi3-Δ
S288C0.01 mM glycolaldehydeDetails: > 10% sensitivity relative to the wild-type (p<0.05)
Jayakody LN, et al. (2011) PMID:20960220
resistance to chemicals: decreased
classical geneticsnull
Allele: ddi3-Δ
S288C0.015% methyl methanesulfonateLi J, et al. (2015) PMID:25847245
Showing 1 to 10 of 13 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


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Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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