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RFA2 / YNL312W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
BUF1 21 , RPA2 , RPA32 22
Feature Type
ORF , Verified
Description
Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; in concert with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication s 1 2 3 4 5 6

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